IL8
Basics
Aliases:
This biomarker is also known as:- Neutrophil-activating protein 1,
- Granulocyte chemotactic protein,
- LYNAP,
- AMCF-I,
- LECT,
- NAF,
- NAP1,
- CXCL8,
- beta-thromboglobulin-like protein,
- IL-8,
- lymphocyte-derived neutrophil-activating factor,
- C-X-C motif chemokine 8,
- interleukin 8,
- Monocyte-derived neutrophil-activating peptide,
- interleukin-8,
- chemokine (C-X-C motif) ligand 8,
- GCP1,
- small inducible cytokine subfamily B, member 8,
- 3-10C,
- MDNCF,
- OTTHUMP00000199825,
- MONAP,
- neutrophil-activating peptide 1,
- NAP-1,
- GCP-1,
- Protein 3-10C,
- LUCT,
- Emoctakin,
- emoctakin,
- T cell chemotactic factor,
- T-cell chemotactic factor,
Description…
Interleukin 8 (IL8) is a member of the CXC chemokine family. This chemokine functions as a chemoattractant, or chemotactic factor, that attracts neutrophils, basophils, and T-cells, but not monocytes. IL8 is one of the major mediators of the inflammatory response, and is involved in neutrophil activation. It is released from several types of cells in response to an inflammatory stimulus. IL8 also functions as an angiogenic factor. The IL8 gene maps to chromosome 4q, and is found in a chemokine gene cluster along with ten other members of the CXC chemokine gene family. There are several N-terminal processed forms that are produced by proteolytic cleavage after secretion from at least peripheral blood monocytes, leukcocytes and endothelial cells. Among the forms are: IL-8(1-77), IL-8(5-77), IL-8(6-77), IL-8(7-77), IL-8(8-77), IL-8(9-77). IL-8(1-77) is generally referred to as interleukin 8. IL-8(6-77) is the most promiment form.
Attributes
| QA State: | Under Review |
|---|---|
| Type: | Protein |
| Short Name: |
Datasets
There are no datasets associated with this biomarker.
Organs
This biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact Heather Kincaid at heather.kincaid@jpl.nasa.gov if you should have access to this biomarker.
Studies
This biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact Heather Kincaid at heather.kincaid@jpl.nasa.gov if you should have access to this biomarker.
Publications
This biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact Heather Kincaid at heather.kincaid@jpl.nasa.gov if you should have access to this biomarker.
Resources
This biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact Heather Kincaid at heather.kincaid@jpl.nasa.gov if you should have access to this biomarker.
