Aliases:This biomarker is also known as:
- chemokine (C-X-C motif) ligand 8,
- Granulocyte chemotactic protein,
- T-cell chemotactic factor,
- beta-thromboglobulin-like protein,
- C-X-C motif chemokine 8,
- lymphocyte-derived neutrophil-activating factor,
- neutrophil-activating peptide 1,
- Neutrophil-activating protein 1,
- small inducible cytokine subfamily B, member 8,
- interleukin 8,
- T cell chemotactic factor,
- Monocyte-derived neutrophil-activating peptide,
- Protein 3-10C,
Interleukin 8 (IL8) is a member of the CXC chemokine family. This chemokine functions as a chemoattractant, or chemotactic factor, that attracts neutrophils, basophils, and T-cells, but not monocytes. IL8 is one of the major mediators of the inflammatory response, and is involved in neutrophil activation. It is released from several types of cells in response to an inflammatory stimulus. IL8 also functions as an angiogenic factor. The IL8 gene maps to chromosome 4q, and is found in a chemokine gene cluster along with ten other members of the CXC chemokine gene family. There are several N-terminal processed forms that are produced by proteolytic cleavage after secretion from at least peripheral blood monocytes, leukcocytes and endothelial cells. Among the forms are: IL-8(1-77), IL-8(5-77), IL-8(6-77), IL-8(7-77), IL-8(8-77), IL-8(9-77). IL-8(1-77) is generally referred to as interleukin 8. IL-8(6-77) is the most promiment form.
There are no datasets associated with this biomarker.