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IL10

Basics

Aliases:
This biomarker is also known as:
  • T-cell growth inhibitory factor,
  • TGIF,
  • cytokine synthesis inhibitory factor,
  • Interleukin-10,
  • CSIF,
  • IL10A,
  • interleukin 10,
  • IL-10,

View in BioMuta

Description…

Interleukin 10, a secreted protein belonging to the IL-10 family, is a cytokine produced primarily by monocytes and to a lesser extent by lymphocytes. It down-regulates the expression of cytokines IL-2, IL-3, TNF and GM-CSF produced by activated macrophages and by helper T-cells, MHC class II Ags, and costimulatory molecules on macrophages.

Attributes

QA State: Curated
Type: Protein
Short Name:

Datasets

There are no datasets associated with this biomarker.

Organs

The following organs have data associated with this biomarker…

Ovary

Attributes

Phase: Two
QA State: Curated

Overview

IL10 alone was not a strong predictor of ovarian cancer.

Performance Comment

Despite many promising new markers for ovarian cancer, CA125 remains the single best biomarker in the phase II and phase III specimens tested in this study.

Studies

This biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact Heather Kincaid at heather.kincaid@jpl.nasa.gov if you should have access to this biomarker.

News

The final report of the 2013 Cancer Biomarkers Bioinformatics Workshop is now available.

Announcement 06/26/2014


Please click here to register for the 9th EDRN Scientific Workshop from September 8-10, 2014, in Bethesda, Maryland. The meeting registration page also has agendas and hotel reservation information.
Announcement 06/05/2014


Funding Opportunity Available

Both RFAs for Molecular and Cellular Characterization of Screen-Detected Lesions have been published.

RFA-CA-14-010.html

and

RFA-CA-14-011.html