Aliases:This biomarker is also known as:
- IGF-binding protein 2,
- Insulin-like growth factor-binding protein 2,
IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell surface receptors. Insulin-like growth factor binding protein 2 (IGFBP2) is overexpressed in ovarian malignant tissues and in the serum and cystic fluid of ovarian cancer patients, suggesting an important role of IGFBP2 in the biology of ovarian cancer.
|QA State:||Under Review|
There are no datasets associated with this biomarker.