Aliases:This biomarker is also known as:
- IGF-binding protein 1,
- Placental protein 12,
- insulin-like growth factor binding protein 1,
- alpha-pregnancy-associated endometrial globulin,
IGFBP1, a secreted protein, is a member of the insulin-like growth factor binding protein (IGFBP) family and encodes a protein with an IGFBP domain and a thyroglobulin type-I domain. It binds both insulin-like growth factors (IGFs) I and II and circulates in the plasma. Binding of this protein prolongs the half-life of the IGFs and alters their interaction with cell surface receptors. IGFBP1 promotes cell migration.
|QA State:||Under Review|
There are no datasets associated with this biomarker.