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HYAL2

Basics

Aliases:
This biomarker is also known as:
  • lysosomal hyaluronidase,
  • EC 3.2.1.35,
  • hyaluronoglucosaminidase-2,
  • LuCa-2,
  • Lung carcinoma protein 2,
  • hyaluronoglucosaminidase 2,
  • hyaluronidase 2,
  • PH-20 homolog,
  • hyal-2,
  • PH20 homolog,
  • LUCA2,
  • hyaluronidase-2,
  • Hyal-2,
  • Hyaluronoglucosaminidase-2,
  • lung carcinoma protein 2,

View in BioMuta

Description…

HYAL2, or hyaluronoglucosaminidase 2, is a weak acid-active hyaluronidase. HYAL2 breaks down hyaluronan, one of the major glycosaminoglycans of the extracellular matrix. Hyaluronan and fragments of hyaluronan are thought to be involved in cell proliferation, migration and differentiation. This hyaluronidase serves as a receptor for the oncogenic virus Jaagsiekte sheep retrovirus. The HYAL2 gene is one of several related genes in a region of chromosome 3p21.3 associated with tumor suppression. There are two known alternatively spliced transcript variants.

Attributes

QA State: Under Review
Type: Protein
Short Name:

Datasets

There are no datasets associated with this biomarker.

Organs

This biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact Heather Kincaid at heather.kincaid@jpl.nasa.gov if you should have access to this biomarker.

Studies

This biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact Heather Kincaid at heather.kincaid@jpl.nasa.gov if you should have access to this biomarker.

Publications

This biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact Heather Kincaid at heather.kincaid@jpl.nasa.gov if you should have access to this biomarker.

Resources

This biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact Heather Kincaid at heather.kincaid@jpl.nasa.gov if you should have access to this biomarker.

News

The final report of the 2013 Cancer Biomarkers Bioinformatics Workshop is now available.

Announcement 03/06/2014

Thank you to everyone who helped make the 27th EDRN Steering Committee Meeting a success. We look forward to seeing everyone at the 9th EDRN Scientific Workshop from September 8-11, 2014 in Washington D.C.

Announcement