HYAL2
Basics
Aliases:
This biomarker is also known as:- PH-20 homolog,
- EC 3.2.1.35,
- PH20 homolog,
- hyaluronoglucosaminidase 2,
- hyaluronidase-2,
- hyaluronidase 2,
- LUCA2,
- LuCa-2,
- hyaluronoglucosaminidase-2,
- lysosomal hyaluronidase,
- hyal-2,
- lung carcinoma protein 2,
- Hyaluronoglucosaminidase-2,
- Lung carcinoma protein 2,
- Hyal-2,
Description…
HYAL2, or hyaluronoglucosaminidase 2, is a weak acid-active hyaluronidase. HYAL2 breaks down hyaluronan, one of the major glycosaminoglycans of the extracellular matrix. Hyaluronan and fragments of hyaluronan are thought to be involved in cell proliferation, migration and differentiation. This hyaluronidase serves as a receptor for the oncogenic virus Jaagsiekte sheep retrovirus. The HYAL2 gene is one of several related genes in a region of chromosome 3p21.3 associated with tumor suppression. There are two known alternatively spliced transcript variants.
Attributes
| QA State: | Under Review |
|---|---|
| Type: | Protein |
| Short Name: |
Datasets
There are no datasets associated with this biomarker.
Organs
This biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact Heather Kincaid at heather.kincaid@jpl.nasa.gov if you should have access to this biomarker.
Studies
This biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact Heather Kincaid at heather.kincaid@jpl.nasa.gov if you should have access to this biomarker.
Publications
This biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact Heather Kincaid at heather.kincaid@jpl.nasa.gov if you should have access to this biomarker.
Resources
This biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact Heather Kincaid at heather.kincaid@jpl.nasa.gov if you should have access to this biomarker.
