Aliases:This biomarker is also known as:
- 17-beta-HSD 10,
- endoplasmic reticulum-associated amyloid beta-peptide-binding protein,
- Short-chain type dehydrogenase/reductase XH98G2,
- 17-beta-hydroxysteroid dehydrogenase 10,
- hydroxyacyl-Coenzyme A dehydrogenase, type II, hydroxyacyl-Coenzyme A dehydrogenase, type II,
- 3-hydroxyacyl-CoA dehydrogenase type II,
- Mitochondrial RNase P protein 2,
- amyloid-beta peptide binding alcohol dehydrogenase,
- AB-binding alcohol dehydrogenase,
- 3-hydroxy-2-methylbutyryl-CoA dehydrogenase,
- 3-hydroxyacyl-CoA dehydrogenase type-2,
- short chain L-3-hydroxyacyl-CoA dehydrogenase type 2,
- hydroxysteroid (17-beta) dehydrogenase 10,
- Endoplasmic reticulum-associated amyloid beta-peptide-binding protein,
- mitochondrial RNase P subunit 2,
- short chain dehydrogenase/reductase family 5C, member 1,
- Mitochondrial ribonuclease P protein 2,
- mental retardation, X-linked, syndromic 10,
- short chain type dehydrogenase/reductase XH98G2,
- EC 188.8.131.52,EC 184.108.40.206,
- mitochondrial ribonuclease P protein 2,
- Type II HADH,
HSD17B10, hydroxysteroid (17-beta) dehydrogenase 10, is a member of the short-chain dehydrogenase/reductase superfamily. HSD17B10 functions in mitochondrial tRNA maturation and catalyzes the oxidation of a wide variety of fatty acids, alcohols, and steroids. The protein is thought to play a role in the development of Alzheimer's disease. There are several alternatively spliced transcript variants, of which only two have been fully sequenced.
There are no datasets associated with this biomarker.
The following organs have data associated with this biomarker…
|QA State:||Under Review|
No additional breast data is available.
HSD17B10 was one of numerous potential early detection biomarkers specific to triple-negative breast cancer in multiple pathways identified.
- Discovery and preliminary confirmation of novel early detection biomarkers for triple-negative breast cancer using preclinical plasma samples from the Women's Health Initiative observational study.
- Development and validation of sandwich ELISA microarrays with minimal assay interference.
- Plasma biomarker profiles differ depending on breast cancer subtype but RANTES is consistently increased.