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HSD17B10

Basics

Aliases:
This biomarker is also known as:
  • MRXS10,
  • Short-chain type dehydrogenase/reductase XH98G2,
  • AB-binding alcohol dehydrogenase,
  • EC 1.1.1.35,EC 1.1.1.178,
  • SDR5C1,
  • HADH2,
  • MRX17,
  • MRX31,
  • 3-hydroxyacyl-CoA dehydrogenase type-2,
  • 17-beta-hydroxysteroid dehydrogenase 10,
  • mitochondrial ribonuclease P protein 2,
  • short chain dehydrogenase/reductase family 5C, member 1,
  • short chain L-3-hydroxyacyl-CoA dehydrogenase type 2,
  • CAMR,
  • mental retardation, X-linked, syndromic 10,
  • XH98G2,
  • Mitochondrial RNase P protein 2,
  • hydroxyacyl-Coenzyme A dehydrogenase, type II, hydroxyacyl-Coenzyme A dehydrogenase, type II,
  • short chain type dehydrogenase/reductase XH98G2,
  • hydroxysteroid (17-beta) dehydrogenase 10,
  • MHBD,
  • Type II HADH,
  • 3-hydroxyacyl-CoA dehydrogenase type II,
  • Endoplasmic reticulum-associated amyloid beta-peptide-binding protein,
  • mitochondrial RNase P subunit 2,
  • 3-hydroxy-2-methylbutyryl-CoA dehydrogenase,
  • DUPXp11.22,
  • ABAD,
  • endoplasmic reticulum-associated amyloid beta-peptide-binding protein,
  • SCHAD,
  • amyloid-beta peptide binding alcohol dehydrogenase,
  • MRPP2,
  • Mitochondrial ribonuclease P protein 2,
  • HCD2,
  • 17-beta-HSD 10,
  • 17b-HSD10,
  • ERAB,

View in BioMuta

Description…

HSD17B10, hydroxysteroid (17-beta) dehydrogenase 10, is a member of the short-chain dehydrogenase/reductase superfamily. HSD17B10 functions in mitochondrial tRNA maturation and catalyzes the oxidation of a wide variety of fatty acids, alcohols, and steroids. The protein is thought to play a role in the development of Alzheimer's disease. There are several alternatively spliced transcript variants, of which only two have been fully sequenced.

Attributes

QA State: Curated
Type: Protein
Short Name:

Datasets

There are no datasets associated with this biomarker.

Organs

The following organs have data associated with this biomarker…

Breast

Attributes

Phase: Two
QA State: Under Review

Overview

No additional breast data is available.

Performance Comment

HSD17B10 was one of numerous potential early detection biomarkers specific to triple-negative breast cancer in multiple pathways identified.

Studies

This biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact Heather Kincaid at heather.kincaid@jpl.nasa.gov if you should have access to this biomarker.

News

The final report of the 2013 Cancer Biomarkers Bioinformatics Workshop is now available.

Announcement 06/26/2014


Please click here to register for the 9th EDRN Scientific Workshop from September 8-10, 2014, in Bethesda, Maryland. The meeting registration page also has agendas and hotel reservation information.
Announcement 06/05/2014


Funding Opportunity Available

Both RFAs for Molecular and Cellular Characterization of Screen-Detected Lesions have been published.

RFA-CA-14-010.html

and

RFA-CA-14-011.html