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GDF15

Basics

Aliases:
This biomarker is also known as:
  • GDF-15,
  • NAG-1,
  • prostate differentiation factor,
  • growth differentiation factor 15,
  • Macrophage inhibitory cytokine 1,
  • NSAID-regulated gene 1 protein,
  • PLAB,
  • MIC-1,
  • NSAID-activated gene 1 protein,
  • NRG-1,
  • Prostate differentiation factor,
  • Placental bone morphogenetic protein,
  • Placental TGF-beta,
  • MIC1,
  • PTGFB,
  • PDF,

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Description…

GDF15, also known as macrophage inhibitory cytokine 1, or MIC1, is a bone morphogenetic protein (BMP) belonging to the transforming growth factor-beta (TGF-beta) superfamily. The bone morphogenetic proteins regulate tissue differentiation and maintenance. GDF15 is a secreted protein that is highly expressed in placenta, with lower levels in prostate and colon and some expression in kidney. Bone morphogenetic protein precursor molecules are cleaved at a dibasic site to release C-terminal domains with 7 conserved cysteines in the mature protein.

Attributes

QA State: Under Review
Type: Protein
Short Name:

Datasets

There are no datasets associated with this biomarker.

Organs

This biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact Heather Kincaid at heather.kincaid@jpl.nasa.gov if you should have access to this biomarker.

Studies

This biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact Heather Kincaid at heather.kincaid@jpl.nasa.gov if you should have access to this biomarker.

Publications

This biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact Heather Kincaid at heather.kincaid@jpl.nasa.gov if you should have access to this biomarker.

Resources

This biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact Heather Kincaid at heather.kincaid@jpl.nasa.gov if you should have access to this biomarker.

News

The final report of the 2013 Cancer Biomarkers Bioinformatics Workshop is now available.

Announcement 03/06/2014

Thank you to everyone who helped make the 27th EDRN Steering Committee Meeting a success. We look forward to seeing everyone at the 9th EDRN Scientific Workshop from September 8-11, 2014 in Washington D.C.

Announcement