Skip to content. | Skip to navigation

National Cancer Institute U.S. National Institutes of Health www.cancer.gov
Sections
Personal tools
Log in
 
You are here: Home › Biomarkers › GDF15

GDF15

Basics

Aliases:
This biomarker is also known as:
  • PDF,
  • prostate differentiation factor,
  • Prostate differentiation factor,
  • NRG-1,
  • Placental bone morphogenetic protein,
  • PLAB,
  • MIC1,
  • MIC-1,
  • PTGFB,
  • NSAID-activated gene 1 protein,
  • Macrophage inhibitory cytokine 1,
  • NAG-1,
  • Placental TGF-beta,
  • NSAID-regulated gene 1 protein,
  • GDF-15,
  • growth differentiation factor 15,

Description…

GDF15 is a bone morphogenetic protein (BMP) belonging to the transforming growth factor-beta (TGF-beta) superfamily. The bone morphogenetic proteins regulate tissue differentiation and maintenance. GDF15 is a secreted protein that is highly expressed in placenta, with lower levels in prostate and colon and some expression in kidney. Bone morphogenetic protein precursor molecules are cleaved at a dibasic site to release C-terminal domains with 7 conserved cysteines in the mature protein.

Attributes

QA State: Under Review
Type: Protein
Short Name:

Datasets

There are no datasets associated with this biomarker.

Organs

This biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact Heather Kincaid at heather.kincaid@jpl.nasa.gov if you should have access to this biomarker.

Studies

This biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact Heather Kincaid at heather.kincaid@jpl.nasa.gov if you should have access to this biomarker.

Publications

This biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact Heather Kincaid at heather.kincaid@jpl.nasa.gov if you should have access to this biomarker.

Resources

This biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact Heather Kincaid at heather.kincaid@jpl.nasa.gov if you should have access to this biomarker.

Announcement