Aliases:This biomarker is also known as:
- basic fibroblast growth factor bFGF,
- fibroblast growth factor 2 (basic),
- Basic fibroblast growth factor,
- heparin-binding growth factor 2,
FGF2, also known as bFGF, is a member of the fibroblast growth factor family. These family members play an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. FGF2 and family members bind heparin and have mitogenic and angiogenic activities. The mRNA for this gene contains multiple polyadenylation sites, and is alternatively translated from non-AUG (CUG) and AUG initiation codons, resulting in five different isoforms with distinct properties.
|QA State:||Under Review|
There are no datasets associated with this biomarker.