Skip to content. | Skip to navigation

National Cancer Institute U.S. National Institutes of Health www.cancer.gov
Sections
Personal tools
Log in
You are here: Home Biomarkers ERCC4

ERCC4

Basics

Aliases:
This biomarker is also known as:
  • DNA repair endonuclease XPF,
  • Xeroderma pigmentosum group F-complementing protein,
  • DNA excision repair protein ERCC-4,
  • excision-repair, complementing defective, in Chinese hamster,
  • EC 3.1.-.-,
  • DNA repair protein complementing XP-F cells,
  • RAD1,
  • XPF,
  • xeroderma pigmentosum, complementation group F,
  • xeroderma pigmentosum group F-complementing protein,
  • excision repair cross-complementing rodent repair deficiency, complementation group 4,
  • ERCC11,

Description…

ERCC4 is a structure-specific DNA repair endonuclease responsible for the 5-prime incision during DNA repair. It forms a complex with ERCC1 and is involved in the 5' incision made during nucleotide excision repair. Mutations in the ERCC4 gene can cause xeroderma pigmentosum complementation group F (XP-F), or xeroderma pigmentosum VI (XP6).

Attributes

QA State: Under Review
Type: Gene
Short Name:

Datasets

There are no datasets associated with this biomarker.

Organs

This biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact Heather Kincaid at heather.kincaid@jpl.nasa.gov if you should have access to this biomarker.

Studies

This biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact Heather Kincaid at heather.kincaid@jpl.nasa.gov if you should have access to this biomarker.

Publications

This biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact Heather Kincaid at heather.kincaid@jpl.nasa.gov if you should have access to this biomarker.

Resources

This biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact Heather Kincaid at heather.kincaid@jpl.nasa.gov if you should have access to this biomarker.