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You are here: Home Biomarkers EGFR

EGFR

Basics

Aliases:
This biomarker is also known as:
  • HER1,
  • cell proliferation-inducing protein 61,
  • PIG61,
  • ERBB,
  • epidermal growth factor receptor (avian erythroblastic leukemia viral (v-erb-b) oncogene homolog),
  • Proto-oncogene c-ErbB-1,
  • ERBB1,
  • mENA,
  • avian erythroblastic leukemia viral (v-erb-b) oncogene homolog,
  • Receptor tyrosine-protein kinase erbB-1,
  • c-erbB-1,
  • Epidermal growth factor receptor,
  • cell growth inhibiting protein 40,

Description…

EGFR is a transmembrane glycoprotein that is a member of the protein kinase superfamily. This protein is a receptor for members of the epidermal growth factor family. EGFR is a cell surface protein that binds to epidermal growth factor. Binding of the protein to a ligand induces receptor dimerization and tyrosine autophosphorylation and leads to cell proliferation. Mutations in this gene are associated with lung cancer.

Attributes

QA State: Under Review
Type: Protein
Short Name:

Datasets

There are no datasets associated with this biomarker.

Organs

This biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact Heather Kincaid at heather.kincaid@jpl.nasa.gov if you should have access to this biomarker.

Studies

This biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact Heather Kincaid at heather.kincaid@jpl.nasa.gov if you should have access to this biomarker.

Publications

This biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact Heather Kincaid at heather.kincaid@jpl.nasa.gov if you should have access to this biomarker.

Resources

This biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact Heather Kincaid at heather.kincaid@jpl.nasa.gov if you should have access to this biomarker.