EGFR
Basics
Aliases:
This biomarker is also known as:- HER1,
- cell proliferation-inducing protein 61,
- PIG61,
- ERBB,
- epidermal growth factor receptor (avian erythroblastic leukemia viral (v-erb-b) oncogene homolog),
- Proto-oncogene c-ErbB-1,
- ERBB1,
- mENA,
- avian erythroblastic leukemia viral (v-erb-b) oncogene homolog,
- Receptor tyrosine-protein kinase erbB-1,
- c-erbB-1,
- Epidermal growth factor receptor,
- cell growth inhibiting protein 40,
Description…
EGFR is a transmembrane glycoprotein that is a member of the protein kinase superfamily. This protein is a receptor for members of the epidermal growth factor family. EGFR is a cell surface protein that binds to epidermal growth factor. Binding of the protein to a ligand induces receptor dimerization and tyrosine autophosphorylation and leads to cell proliferation. Mutations in this gene are associated with lung cancer.
Attributes
| QA State: | Under Review |
|---|---|
| Type: | Protein |
| Short Name: |
Datasets
There are no datasets associated with this biomarker.
Organs
This biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact Heather Kincaid at heather.kincaid@jpl.nasa.gov if you should have access to this biomarker.
Studies
This biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact Heather Kincaid at heather.kincaid@jpl.nasa.gov if you should have access to this biomarker.
Publications
This biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact Heather Kincaid at heather.kincaid@jpl.nasa.gov if you should have access to this biomarker.
Resources
This biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact Heather Kincaid at heather.kincaid@jpl.nasa.gov if you should have access to this biomarker.
