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EGFR

Basics

Aliases:
This biomarker is also known as:
  • ERBB1,
  • Epidermal growth factor receptor,
  • HER1,
  • PIG61,
  • mENA,
  • epidermal growth factor receptor (erythroblastic leukemia viral (v-erb-b) oncoge,
  • ERBB,
  • c-erbB-1,
  • Receptor tyrosine-protein kinase erbB-1,

Description…

EGFR is a transmembrane glycoprotein that is a member of the protein kinase superfamily. This protein is a receptor for members of the epidermal growth factor family. EGFR is a cell surface protein that binds to epidermal growth factor. Binding of the protein to a ligand induces receptor dimerization and tyrosine autophosphorylation and leads to cell proliferation. Mutations in this gene are associated with lung cancer.

Attributes

QA State: Under Review
Type: Protein
Short Name:

Datasets

There are no datasets associated with this biomarker.

Organs

This biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact Heather Kincaid at heather.kincaid@jpl.nasa.gov if you should have access to this biomarker.

Studies

This biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact Heather Kincaid at heather.kincaid@jpl.nasa.gov if you should have access to this biomarker.

Publications

This biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact Heather Kincaid at heather.kincaid@jpl.nasa.gov if you should have access to this biomarker.

Resources

This biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact Heather Kincaid at heather.kincaid@jpl.nasa.gov if you should have access to this biomarker.

Document Actions
Steering Committee Meeting

Join us in Arizona in March for EDRN's 24th Steering Committee Meeting.

Announcement 12/14/2011

On Tuesday, January 24, 2012 the NCI-funded Alliance of Glycobiologists for Cancer Detection and Cancer Risk will host a symposium entitled: Interfacing Glycoscience with Disease and Clinical Practice. The symposium will take place at the Natcher Conference Center, NIH Campus, from 8:30 AM until 5:00 PM.
Announcement

NASA has selected the EDRN Informatics Team to receive a Group Achievement Award. The award will be given to the teams at NCI, DMCC, Dartmouth and JPL. These are NASA-wide awards and selected by an awards committee appointed by NASA Headquarters. The citation is as follows: For the innovative and pioneering use of NASA data system technologies to construct a national bioinformatics network of cancer biomarker research.