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CYP24A1

Basics

Aliases:
This biomarker is also known as:
  • CP24,
  • Cytochrome P450 24A1,
  • 1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial,
  • CYP24,
  • EC 1.14.13.126,
  • vitamin D 24-hydroxylase,
  • HCAI,
  • exo-mitochondrial protein,
  • cytochrome P450, family 24, subfamily A, polypeptide 1,
  • Cytochrome P450-CC24,
  • P450-CC24,
  • 24-OHase,
  • 1,25-@dihydroxyvitamin D3 24-hydroxylase,
  • Vitamin D(3) 24-hydroxylase,
  • cytochrome P450, subfamily XXIV (vitamin D 24-hydroxylase),

View in BioMuta

Description…

The CYP24A1 protein is a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. CYP24A1 is involved in maintaining calcium homeostasis and catalyzes the NADPH-dependent 24-hydroxylation of calcidiol (25-hydroxyvitamin D3) and calcitriol (1-alpha,25-dihydroxyvitamin D3). Several different isoforms exist, encoded by alternatively spliced transcript variants.

Attributes

QA State: Under Review
Type: Gene
Short Name:

Datasets

There are no datasets associated with this biomarker.

Organs

This biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact Heather Kincaid at heather.kincaid@jpl.nasa.gov if you should have access to this biomarker.

Studies

This biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact Heather Kincaid at heather.kincaid@jpl.nasa.gov if you should have access to this biomarker.

Publications

This biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact Heather Kincaid at heather.kincaid@jpl.nasa.gov if you should have access to this biomarker.

Resources

This biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact Heather Kincaid at heather.kincaid@jpl.nasa.gov if you should have access to this biomarker.

Announcement 09/14/2014

Thank you to everyone who helped make the 9th EDRN Scientific Workshop a success. We look forward to seeing everyone at the 28th EDRN Steering Committee Meeting from March 31-April 2, 2015, in Atlanta, GA.

Announcement 06/05/2014


Funding Opportunity Available

Both RFAs for Molecular and Cellular Characterization of Screen-Detected Lesions have been published.

RFA-CA-14-010.html

and

RFA-CA-14-011.html