Aliases:This biomarker is also known as:
- Hypertrophic chondrocyte-specific protein 24,
- IGF-binding protein 8,
- CCN family member 2,
- connective tissue growth factor,
- Insulin-like growth factor-binding protein 8,
CTGF, a major connective tissue mitoattractant secreted by vascular endothelial cells, promotes proliferation and differentiation of chondrocytes. It mediates heparin- and divalent cation-dependent cell adhesion in many cell types including fibroblasts, myofibroblasts, endothelial and epithelial cells. It enhances fibroblast growth factor-induced DNA synthesis. CTGF is expressed in bone marrow and thymic cells. It is also expressed one of two Wilms tumors tested.
|QA State:||Under Review|
There are no datasets associated with this biomarker.