Aliases:This biomarker is also known as:
- Creatine kinase M-type,
- creatine kinase-M,
- creatine kinase, muscle,
- Creatine kinase M chain,
CKM is a cytoplasmic enzyme involved in energy homeostasis and is an important serum marker for myocardial infarction. It reversibly catalyzes the transfer of phosphate between ATP and various phosphogens, such as creatine phosphate. Creatine kinase isoenzymes play a central role in energy transduction in tissues with large, fluctuating energy demands, such as skeletal muscle, heart, brain and spermatozoa. Structurally, CKM exists primarily as a homodimer in striated muscle and myocardium, and as a heterodimer in brain and in heart, as well as other tissues. CKM is a member of the ATP:guanido phosphotransferase family.
|QA State:||Under Review|
There are no datasets associated with this biomarker.