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CEACAM5

Basics

Aliases:
This biomarker is also known as:
  • Carcinoembryonic antigen,
  • DKFZp781M2392,
  • CD66e,
  • carcinoembryonic antigen-related cell adhesion molecule 5,
  • Meconium antigen 100,
  • CD_antigen=CD66e,
  • CEA,

View in BioMuta

Description…

CEA is a cell surface glycoprotein that plays a role in cell adhesion and in intracellular signaling. It is a receptor for E.coli Dr adhesins.

Attributes

QA State: Curated
Type: Protein
Short Name:

Datasets

There are no datasets associated with this biomarker.

Organs

The following organs have data associated with this biomarker…

Lung

Attributes

Phase: Two
QA State: Under Review

Overview

Performance Comment

Ovary

Attributes

Phase: Two
QA State: Under Review

Overview

CEACAM5 is a member of the carcinoembryonic antigen (CEA) family. The carcinoembryonic proteins are found normally in the blood of a fetus. The CEA proteins are also found in the blood of some people who have certain types of tumors, such as colorectal, pancreas, breast, ovary, or lung. CEA levels are not usually elevated in early cancer, and in some cancers are not elevated at all.

Performance Comment

Despite many promising new markers for ovarian cancer, CA125 remains the single best biomarker in the phase II and phase III specimens tested in this study.

Studies

This biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact Heather Kincaid at heather.kincaid@jpl.nasa.gov if you should have access to this biomarker.

News

The final report of the 2013 Cancer Biomarkers Bioinformatics Workshop is now available.

Announcement 06/26/2014


Please click here to register for the 9th EDRN Scientific Workshop from September 8-10, 2014, in Bethesda, Maryland. The meeting registration page also has agendas and hotel reservation information.
Announcement 06/05/2014


Funding Opportunity Available

Both RFAs for Molecular and Cellular Characterization of Screen-Detected Lesions have been published.

RFA-CA-14-010.html

and

RFA-CA-14-011.html