Aliases:This biomarker is also known as:
- colon cancer-specific antigen 2,
CCSA-2 is a potential serum-based marker for colon cancer detection with high sensitivity and specificity. Receiver operating characteristic analyses were used to measure the sensitivity and specificity of CCSA-2. CCSA-2 at a cutoff of 10.8 mug/mL has overall specificity of 78.4% [95% confidence interval (95% CI), 67.3-87.1%] and sensitivity of 97.3% (95% CI, 85.8-99.5%) in separating individuals with advanced adenomas and colorectal cancer from normal, hyperplastic, and nonadvanced adenoma populations. The receiver operating characteristic curve for CCSA-2 has an area under the curve of 0.90 (95% CI, 0.83-0.95).
|QA State:||Under Review|
There are no datasets associated with this biomarker.