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CCL5

Basics

Aliases:
This biomarker is also known as:
  • C-C motif chemokine 5,
  • small inducible cytokine A5 (RANTES),
  • D17S136E,
  • RANTES,
  • small inducible cytokine subfamily A (Cys-Cys), member 5,
  • MGC17164,
  • SISd,
  • SCYA5,
  • eoCP,
  • T-cell-specific protein RANTES,
  • Small-inducible cytokine A5,
  • Eosinophil chemotactic cytokine,
  • T cell-specific protein P228,
  • SIS-delta,
  • chemokine (C-C motif) ligand 5,
  • T-cell specific protein p288,
  • beta-chemokine RANTES,
  • small-inducible cytokine A5,
  • TCP228,
  • regulated upon activation, normally T-expressed, and presumably secreted,
  • t cell-specific protein P228,
  • EoCP,
  • eosinophil chemotactic cytokine,

View in BioMuta

Description…

CCL5 (RANTES) is a chemokine, a subfamily of cytokines. Chemokines form a superfamily of secreted proteins involved in immunoregulatory and inflammatory processes. CCL5 is a chemoattractant for blood monocytes, memory T-helper cells and eosinophils and causes the release of histamine from basophils and activates eosinophils. There are several transcript variants that encode different isoforms.

Attributes

QA State: Curated
Type: Protein
Short Name:

Datasets

There are no datasets associated with this biomarker.

Organs

The following organs have data associated with this biomarker…

Breast

Attributes

Phase: Two
QA State: Under Review

Overview

The chemokine CCL5 (RANTES), a major monocyte chemoattractant expressed by breast tumor cells, has been implicated in the progression of breast cancer.

Performance Comment

CCL5 (RANTES) was one of numerous potential early detection biomarkers specific to triple-negative breast cancer in multiple pathways identified.

Studies

This biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact Heather Kincaid at heather.kincaid@jpl.nasa.gov if you should have access to this biomarker.

News

The final report of the 2013 Cancer Biomarkers Bioinformatics Workshop is now available.

Announcement 06/26/2014


Please click here to register for the 9th EDRN Scientific Workshop from September 8-10, 2014, in Bethesda, Maryland. The meeting registration page also has agendas and hotel reservation information.
Announcement 06/05/2014


Funding Opportunity Available

Both RFAs for Molecular and Cellular Characterization of Screen-Detected Lesions have been published.

RFA-CA-14-010.html

and

RFA-CA-14-011.html