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CCL27

Basics

Aliases:
This biomarker is also known as:
  • ESKINE,
  • IL-11 R-alpha-locus chemokine,
  • Skinkine,
  • C-C motif chemokine 27,
  • IL-11 Ralpha-locus chemokine,
  • skinkine,
  • chemokine (C-C motif) ligand 27,
  • Cutaneous T-cell-attracting chemokine,
  • small inducible cytokine subfamily A (Cys-Cys), member 27,
  • CTACK,
  • PESKY,
  • Small-inducible cytokine A27,
  • CC chemokine ILC,
  • ALP,
  • cutaneous T-cell-attracting chemokine,
  • SCYA27,
  • ESkine,
  • cutaneous T-cell attracting chemokine,
  • ILC,
  • CTAK,
  • small-inducible cytokine A27,

View in BioMuta

Description…

CCL27 is a member of the CC cytokine family, and is involved in immunoregulatory and inflammatory processes. CC cytokines are characterized by two adjacent cysteines. CCL27 functions as a chemotactic factor that attracts skin-associated memory T-lymphocytes. CCL27 may also play a role in mediating homing of lymphocytes to cutaneous sites. CCL27 binds specifically to chemokine receptor 10 (CCR10).

Attributes

QA State: Curated
Type: Protein
Short Name:

Datasets

There are no datasets associated with this biomarker.

Organs

The following organs have data associated with this biomarker…

Breast

Attributes

Phase: Two
QA State: Under Review

Overview

CCL27 was present at higher levels among cases compared to controls with reasonable AUC values.

Performance Comment

CCL27 was one of numerous potential early detection biomarkers specific to triple-negative breast cancer in multiple pathways identified.

Studies

This biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact Heather Kincaid at heather.kincaid@jpl.nasa.gov if you should have access to this biomarker.

News

The final report of the 2013 Cancer Biomarkers Bioinformatics Workshop is now available.

Announcement 06/26/2014


Please click here to register for the 9th EDRN Scientific Workshop from September 8-10, 2014, in Bethesda, Maryland. The meeting registration page also has agendas and hotel reservation information.
Announcement 06/05/2014


Funding Opportunity Available

Both RFAs for Molecular and Cellular Characterization of Screen-Detected Lesions have been published.

RFA-CA-14-010.html

and

RFA-CA-14-011.html