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APCS

Basics

Aliases:
This biomarker is also known as:
  • pentaxin-related,
  • 9.5S alpha-1-glycoprotein,
  • amyloid P component, serum,
  • PTX2,
  • Serum amyloid P-component,
  • SAP,
  • MGC88159,

View in BioMuta

Description…

APCS, a secreted glycoprotein found in serum and urine, interacts with DNA and histones and may scavenge nuclear material released from damaged circulating cells. It is thought to control the degradation of chromatin and has been demonstrated to bind to apoptotic cells at an early stage, which raises the possibility that it is involved in dealing with apoptotic cells in vivo. APCS may also function as a calcium-dependent lectin. APCS is a member of the pentaxin family of proteins, which characteristically bind two calcium ions per subunit and have a a discoid arrangement of 5 non-covalently bound subunits.

Attributes

QA State: Under Review
Type: Protein
Short Name:

Datasets

There are no datasets associated with this biomarker.

Organs

This biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact Heather Kincaid at heather.kincaid@jpl.nasa.gov if you should have access to this biomarker.

Studies

This biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact Heather Kincaid at heather.kincaid@jpl.nasa.gov if you should have access to this biomarker.

Publications

This biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact Heather Kincaid at heather.kincaid@jpl.nasa.gov if you should have access to this biomarker.

Resources

This biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact Heather Kincaid at heather.kincaid@jpl.nasa.gov if you should have access to this biomarker.

News

The final report of the 2013 Cancer Biomarkers Bioinformatics Workshop is now available.

Announcement 06/26/2014


Please click here to register for the 9th EDRN Scientific Workshop from September 8-10, 2014, in Bethesda, Maryland. The meeting registration page also has agendas and hotel reservation information.
Announcement 06/05/2014


Funding Opportunity Available

Both RFAs for Molecular and Cellular Characterization of Screen-Detected Lesions have been published.

RFA-CA-14-010.html

and

RFA-CA-14-011.html