Aliases:This biomarker is also known as:
- Lipocortin II,
- Annexin II,
- Protein I,
- Annexin A2,
- Calpactin-1 heavy chain,
- Placental anticoagulant protein IV,
- Calpactin I heavy chain,
ANXA2, a member of the annexin family, is a calcium-dependent phospholipid-binding protein that plays a role in the regulation of cellular growth and in signal transduction pathways. Its affinity for calcium is greatly enhanced by anionic phospholipids, and it binds two calcium ions with high affinity. ANXA2 may be involved in heat-stress response. This protein functions as an autocrine factor which heightens osteoclast formation and bone resorption. It may also cross-link plasma membrane phospholipids with actin and the cytoskeleton and be involved with exocytosis.
|QA State:||Under Review|
There are no datasets associated with this biomarker.