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ALDH1A2

Basics

Aliases:
This biomarker is also known as:
  • Aldehyde dehydrogenase family 1 member A2,
  • Retinaldehyde-specific dehydrogenase type 2,
  • RALDH 2,
  • RALDH2-T,
  • RALDH2,
  • RALDH(II),
  • aldehyde dehydrogenase 1 family, member A2,
  • retinal dehydrogenase 2,
  • retinaldehyde-specific dehydrogenase type 2,
  • RalDH2,
  • EC 1.2.1.36,

View in BioMuta

Description…

aldehyde dehydrogenase 1 family, member A2

Attributes

QA State: Curated
Type: Gene
Short Name:

Datasets

There are no datasets associated with this biomarker.

Organs

The following organs have data associated with this biomarker…

Prostate

Attributes

Phase: One
QA State: Curated

Overview

ALDH1A2 is a candidate tumor suppressor in prostate cancer.

Performance Comment

Significance Analysis of Microarray (SAM) was used to develop a 7-gene classifier. The overall prediction accuracy and sensitivity is 71% and 76%, respectively. The inclusion of the Gleason sum to the seven-gene classifier raised the prediction accuracy and sensitivity to 83% and 76% respectively This prognostic signature is closely associated with biochemical recurrence in patients after radical prostatectomy. The seven genes are: RRAGD, PQBP1, HIST1H2BC, ALDH1A2, TRIM22, RBPMS, HSPB8.

Studies

This biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact Heather Kincaid at heather.kincaid@jpl.nasa.gov if you should have access to this biomarker.

News

Maintenance Notice: EDRN applications undergoing maintenance 2014-09-15 through the 16th. During this time, logins to this site will be unavailable.

Announcement 06/05/2014


Funding Opportunity Available

Both RFAs for Molecular and Cellular Characterization of Screen-Detected Lesions have been published.

RFA-CA-14-010.html

and

RFA-CA-14-011.html
Announcement