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ACTR3

Basics

Aliases:
This biomarker is also known as:
  • ARP3 (actin-related protein 3, yeast) homolog,
  • ARP3,
  • actin-like protein 3,
  • Actin-like protein 3,
  • P61158,
  • ARP3 actin-related protein 3 homolog (yeast),
  • actin-related protein 3,

View in BioMuta

Description…

The ACTR3 protein is a component of the ARP2/3 complex, which is essential to cell shape and motility.

Attributes

QA State: Curated
Type: Protein
Short Name:

Datasets

There are no datasets associated with this biomarker.

Organs

The following organs have data associated with this biomarker…

Ovary

Attributes

Phase: Two
QA State: Under Review

Overview

ACTR3 is a tumor vascular marker (TVM) identified through expression profiling of ovarian cancer vascular cells.

Performance Comment

In PMID:21617380, 13 tumor vascular markers (TVMs) from 50 candidates identified through expression profiling of ovarian cancer vascular cells and selected to be either transmembrane or secreted, and to be either absent or expressed at low levels in normal tissues while overexpressed in tumors, based on analysis of 1,110 normal and tumor tissues from publicly available Affymetrix microarray data were investigated. ACTR3 was not selected to be studied further.

Studies

This biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact Heather Kincaid at heather.kincaid@jpl.nasa.gov if you should have access to this biomarker.

Announcement 09/14/2014

Thank you to everyone who helped make the 9th EDRN Scientific Workshop a success. We look forward to seeing everyone at the 28th EDRN Steering Committee Meeting from March 31-April 2, 2015, in Atlanta, GA.

Announcement 06/05/2014


Funding Opportunity Available

Both RFAs for Molecular and Cellular Characterization of Screen-Detected Lesions have been published.

RFA-CA-14-010.html

and

RFA-CA-14-011.html