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This biomarker is also known as:
  • iron-responsive element binding protein 1,
  • EC,
  • aconitate hydratase,
  • Aconitase,
  • ferritin repressor protein,
  • IREBP1,
  • Iron regulatory protein 1,
  • citrate hydro-lyase,
  • iron-responsive element-binding protein 1,
  • IREB1,
  • IREBP,
  • Ferritin repressor protein,
  • cytoplasmic aconitate hydratase,
  • Iron-responsive element-binding protein 1,
  • ACONS,
  • IRE-BP 1,
  • iron regulatory protein 1,
  • aconitase 1, soluble,
  • Citrate hydro-lyase,
  • IRP1,

View in BioMuta


aconitase 1, soluble


QA State: Curated
Type: Gene
Short Name:


There are no datasets associated with this biomarker.


The following organs have data associated with this biomarker…



Phase: One
QA State: Under Review


No additional prostate data available.

Performance Comment

This gene is part of a 114-gene set that comprises a stroma-specific classifier for nearby prostate tumors. Gene expression changes in stroma have been identified that can detect tumor nearby. This classifier predicted the tumor status of patients using tumor-free samples with an average accuracy of 97% (sensitivity = 98% and specificity = 88%) whereas classifiers trained with sets of 100 randomly generated genes had no diagnostic value. These results indicate that the prostate cancer microenvironment exhibits reproducible changes useful for categorizing the presence of tumor in patients when a prostate sample is derived from near the tumor but does not contain any recognizable tumor. (PMID:21459804)


This biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact Heather Kincaid at if you should have access to this biomarker.


No associated resources found.

Announcement 09/14/2014

Thank you to everyone who helped make the 9th EDRN Scientific Workshop a success. We look forward to seeing everyone at the 28th EDRN Steering Committee Meeting from March 31-April 2, 2015, in Atlanta, GA.

Announcement 06/05/2014

Funding Opportunity Available

Both RFAs for Molecular and Cellular Characterization of Screen-Detected Lesions have been published.