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ZFP36L1

Basics

Aliases:
This biomarker is also known as:
  • zinc finger protein, C3H type, 36-like 1,
  • cMG1,
  • EGF-response factor 1,
  • BERG36,
  • ERF1,
  • BRF1,
  • TIS11B,
  • ERF-1,
  • RNF162B,
  • zinc finger protein 36, C3H1 type-like 1,
  • Protein TIS11B,
  • Butyrate response factor 1,
  • Berg36,
  • butyrate response factor 1,
  • early response factor Berg36,
  • zinc finger protein 36, C3H type-like 1,

View in BioMuta

Description…

ZFP36L1 is a member of the TIS11 family of early response genes, which are induced by various agonists such as the phorbol ester TPA and the polypeptide mitogen EGF. The ZFP36L1 gene is well conserved across species and has a promoter that contains motifs seen in other early-response genes. ZFP36L1 contains a putative zinc finger domain with a repeating cys-his motif. ZFP36L1 is believed to be a nuclear transcription factor most likely functioning in regulating the response to growth factors. Different isoforms encoded by alternatively spliced transcript variants have been isolated.

Attributes

QA State: Curated
Type: Protein
Short Name:
HGNC Name: ZFP36L1

Datasets

There are no datasets associated with this biomarker.

Organs

The following organs have data associated with this biomarker…

Breast

Attributes

Phase: Two
QA State: Under Review

Overview

No additional breast data available.

Performance Comment

ZFP36L1 was one of numerous potential early detection biomarkers specific to triple-negative breast cancer in multiple pathways identified.

Studies

This biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact Heather Kincaid at heather.kincaid@jpl.nasa.gov if you should have access to this biomarker.

Announcement 10/07/2014

EDRN Patient Advocates will host an EDRN Advocacy Educational Webinar, Biomarkers for Prostate Cancer Detection and Monitoring, on Monday, January 12th, 2015, at 1 p.m. EDT / 10 a.m. PDT. Registration is not required for this. Please click for more information.
Announcement 09/14/2014

Thank you to everyone who helped make the 9th EDRN Scientific Workshop a success. We look forward to seeing everyone at the 28th EDRN Steering Committee Meeting from March 31-April 2, 2015, in Atlanta, GA.