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XPOT

Basics

Aliases:
This biomarker is also known as:
  • exportin-T,
  • XPO3,
  • exportin, tRNA (nuclear export receptor for tRNAs),
  • Exportin(tRNA),
  • exportin(tRNA),
  • tRNA exportin,

View in BioMuta

Description…

XPOT, or exportin-T, belongs to the RAN-GTPase exportin family. This protein facilitates export of tRNA from the nucleus to the cytoplasm. XPOT shuttles between the nucleus and the cytoplasm, transporting the aminoacylated tRNAs out of the nucleus, and returning back for another round.

Attributes

QA State: Curated
Type: Protein
Short Name:
HGNC Name: XPOT

Datasets

There are no datasets associated with this biomarker.

Organs

The following organs have data associated with this biomarker…

Breast

Attributes

Phase: Two
QA State: Under Review

Overview

No additional breast data available.

Performance Comment

XPOT was one of numerous potential early detection biomarkers specific to triple-negative breast cancer in multiple pathways identified.

Studies

This biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact Heather Kincaid at heather.kincaid@jpl.nasa.gov if you should have access to this biomarker.

2015 EDRN PI Orientation

The New and Continuing EDRN Principal Investigator Orientation will take place October 15–16, 2015 in Bethesda, Maryland.

Announcement 06/30/2015

A funding opportunity for a new pancreatic cancer initiative, called The Pancreatic Cancer Detection Consortium (U01), has been released. For more information, please go to http://grants.nih.gov /grants/guide/ pa-files/ PAR-15-289.html.

Announcement 04/08/2015

Thank you to everyone who made the 29th EDRN Steering Committee Meeting a success. The orientation for new and continuing EDRN PIs will be held October 15-16, 2015 on the NCI campus. More information will be available later this summer.