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TNFRSF1A

Basics

Aliases:
This biomarker is also known as:
  • Tumor Necrosis Factor Receptor Type I,
  • MS5,
  • TNF-R,
  • TNFR1,
  • TNFR1-D2,
  • Tumor Necrosis Factor-Alpha Receptor,
  • TNFR-I,
  • TNF-R1,
  • Tumor Necrosis Factor Binding Protein 1,
  • CD120a Antigen,
  • Tumor Necrosis Factor Receptor Type 1,
  • Tumor Necrosis Factor Receptor 1,
  • TNFR60,
  • P60,
  • TNFAR,
  • P55,
  • FPF,
  • Tumor Necrosis Factor Receptor Superfamily Member 1A,
  • CD120a,
  • P55-R,
  • TNF-R55,
  • Tumor Necrosis Factor Receptor 1A Isoform Beta,
  • TBP1,
  • Tumor Necrosis Factor Receptor Superfamily, Member 1A,
  • TNF-RI,

View in BioMuta

Description…

TNFRSF1A, one of the major receptors for the TNF-alpha, is a member of the TNF-receptor superfamily. This protein activates NF-kappaB, mediates apoptosis, and functions as a regulator of inflammation. TNFRSF1A has been shown to interact with adaptor proteins TRADD and TRAF2 and antiapoptotic protein BCL2-associated athanogene 4 (BAG4/SODD). TNFRSF1A is involved in activating at least two distinct signaling cascades, apoptosis and NF-kappa-B signaling.

Attributes

QA State: Under Review
Type: Protein
Short Name:
HGNC Name: TNFRSF1A

Datasets

There are no datasets associated with this biomarker.

Organs

This biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact Heather Kincaid at heather.kincaid@jpl.nasa.gov if you should have access to this biomarker.

Studies

This biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact Heather Kincaid at heather.kincaid@jpl.nasa.gov if you should have access to this biomarker.

Publications

This biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact Heather Kincaid at heather.kincaid@jpl.nasa.gov if you should have access to this biomarker.

Resources

This biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact Heather Kincaid at heather.kincaid@jpl.nasa.gov if you should have access to this biomarker.

2015 Steering Committee Meeting

The next EDRN Steering Committee Meeting will take place March 31st through April 2nd, 2015, in Atlanta, Georgia.

Announcement 12/02/2014

New Round of EDRN FOAs

The RFAs for EDRN have been released:
- Biomarker Developmental Laboratories (U01),
- Clinical Validation Centers (U01),
- Biomarker Reference Laboratories (U24),
- Data Management and Coordinating Center (U24).

EDRN Renewal flyer NOTE-New receipt deadline for applications submitted for all EDRN FOAs is January 20, 2015, by 5:00 PM local time of applicant organization.

There will be a Pre-Application webinar to discuss each of the four individual EDRN FOAs on Tuesday, December 2nd, 2014, from 1pm-5pm (Eastern). Potential applicants interested in participating in the webinar should send a message to Dr. Sharmistha Ghosh (ghoshjanjigias@mail.nih.gov) no later than 5:00 p.m. (EST) November 21, 2014. Please mention the FOA of interest in the subject line.

Announcement 10/07/2014

EDRN Patient Advocates will host an EDRN Advocacy Educational Webinar, Biomarkers for Prostate Cancer Detection and Monitoring, on Monday, January 12th, 2015, at 1 p.m. EDT / 10 a.m. PDT. Registration is not required for this. Please click for more information.