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STAT6

Basics

Aliases:
This biomarker is also known as:
  • signal transducer and activator of transcription 6, interleukin-4 induced,
  • D12S1644,
  • IL-4-STAT,
  • IL-4 Stat,
  • STAT6B,
  • STAT6C,
  • STAT, interleukin4-induced,
  • transcription factor IL-4 STAT,
  • signal transducer and activator of transcription 6,

View in BioMuta

Description…

STAT6 is a member of the STAT family of transcription factors. STAT family members are phosphorylated by the receptor associated kinases in response to cytokines and growth factors and are involved in signal transduction and activation of transcription. There are several transcript variants produced by alternative splicing.

Attributes

QA State: Curated
Type: Protein
Short Name:
HGNC Name: STAT6

Datasets

There are no datasets associated with this biomarker.

Organs

The following organs have data associated with this biomarker…

Breast

Attributes

Phase: Two
QA State: Under Review

Overview

The transcription factor STAT6 is a member of a family of DNA binding proteins. STAT6 has been shown to be a critical cell differentiation modulator in breast cancer cells.

Performance Comment

STAT6 was one of numerous potential early detection biomarkers specific to triple-negative breast cancer in multiple pathways identified.

Studies

This biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact Heather Kincaid at heather.kincaid@jpl.nasa.gov if you should have access to this biomarker.

2015 Steering Committee Meeting

The next EDRN Steering Committee Meeting will take place March 31st through April 2nd, 2015, in Atlanta, Georgia.

Announcement 02/12/2015

Please register for the 29th EDRN Steering Committee Meeting in Atlanta, GA from March 31-April 2, 2015. The registration page has information about booking hotel rooms and a draft agenda of the meeting.

Announcement