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SERPINA1

Basics

Aliases:
This biomarker is also known as:
  • Alpha-1-antiproteinase,
  • Alpha-1 protease inhibitor,
  • alpha-1-antitrypsin null,
  • hAAT,
  • MGC9222,
  • alpha1AT,
  • A1A,
  • serine (or cysteine) proteinase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1,
  • serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1,
  • PI1,
  • A1AT,
  • PRO2275,
  • protease inhibitor 1 (anti-elastase), alpha-1-antitrypsin,
  • AAT,
  • MGC23330,
  • alpha-1-antitrypsin,
  • PI,
  • Serpin A1,
  • serine (or cysteine) proteinase inhibitor, clade A, member 1,

View in BioMuta

Description…

Alpha-1-antitrypsin is secreted and is an extracellular serine protease inhibitor whose targets include elastase, plasmin, thrombin, trypsin, chymotrypsin, and plasminogen activator. Defects in this gene can cause emphysema or liver disease. Elevation of alpha1-AT serum levels have been observed in the course of a large number of malignant diseases. Several transcript variants encoding the same protein have been found for this gene.

Attributes

QA State: Under Review
Type: Protein
Short Name:
HGNC Name: SERPINA1

Datasets

There are no datasets associated with this biomarker.

Organs

This biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact Heather Kincaid at heather.kincaid@jpl.nasa.gov if you should have access to this biomarker.

Studies

This biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact Heather Kincaid at heather.kincaid@jpl.nasa.gov if you should have access to this biomarker.

Publications

This biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact Heather Kincaid at heather.kincaid@jpl.nasa.gov if you should have access to this biomarker.

Resources

This biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact Heather Kincaid at heather.kincaid@jpl.nasa.gov if you should have access to this biomarker.

2015 EDRN PI Orientation

The New and Continuing EDRN Principal Investigator Orientation will take place October 15–16, 2015 in Bethesda, Maryland.

Announcement 04/08/2015

Thank you to everyone who made the 29th EDRN Steering Committee Meeting a success. The orientation for new and continuing EDRN PIs will be held October 15-16, 2015 on the NCI campus. More information will be available later this summer.

Announcement