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SDC1

Basics

Aliases:
This biomarker is also known as:
  • SDC,
  • heparan sulfate proteoglycan fibroblast growth factor receptor,
  • P18827,
  • syndecan-1,
  • syndecan proteoglycan 1,
  • CD138 antigen,
  • syndecan 1,
  • syndecan,
  • CD138,

View in BioMuta

Description…

SDC1 is a transmembrane (type I) heparan sulfate proteoglycan and is a member of the syndecan proteoglycan family. The SDC1 protein functions as an integral membrane protein and participates in cell proliferation, cell migration and cell-matrix interactions via its receptor for extracellular matrix proteins.

Attributes

QA State: Curated
Type: Protein
Short Name:
HGNC Name: SDC1

Datasets

There are no datasets associated with this biomarker.

Organs

The following organs have data associated with this biomarker…

Ovary

Attributes

Phase: Two
QA State: Under Review

Overview

SDC1 was shown to localize to vascular-like structures in ovarian cancer but not in normal ovaries.

Performance Comment

SDC1 was one of 13 genes out of 50 selected for further validation in PMID:21617380.

Studies

This biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact Heather Kincaid at heather.kincaid@jpl.nasa.gov if you should have access to this biomarker.

Announcement 10/07/2014

EDRN Patient Advocates will host an EDRN Advocacy Educational Webinar, Biomarkers for Prostate Cancer Detection and Monitoring, on Monday, January 12th, 2015, at 1 p.m. EDT / 10 a.m. PDT. Registration is not required for this. Please click for more information.
Announcement 09/14/2014

Thank you to everyone who helped make the 9th EDRN Scientific Workshop a success. We look forward to seeing everyone at the 28th EDRN Steering Committee Meeting from March 31-April 2, 2015, in Atlanta, GA.