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RHOA

Basics

Aliases:
This biomarker is also known as:
  • Rho12,
  • ARHA,
  • transforming protein RhoA,
  • ras homolog gene family, member A,
  • Aplysia ras-related homolog 12,
  • oncogene RHO H12,
  • RHO12,
  • small GTP binding protein RhoA,
  • Rho cDNA clone 12,
  • h12,
  • ARH12,
  • RhoA,
  • rho cDNA clone 12,
  • ras homolog family member A,
  • RHOH12,

View in BioMuta

Description…

RHOA is a member of the small GTPase superfamily. RHO family GTPases are involved in many basic cellular processes that influence cell proliferation, differentiation, motility, adhesion, survival, or secretion. RHOA regulates a signal transduction pathway linking plasma membrane receptors to the assembly of focal adhesions and actin stress fibers.

Attributes

QA State: Curated
Type: Protein
Short Name:
HGNC Name: RHOA

Datasets

There are no datasets associated with this biomarker.

Organs

The following organs have data associated with this biomarker…

Breast

Attributes

Phase: Two
QA State: Under Review

Overview

RHOA has been shown to be involved in hypoxia-inducible factor-mediated RHOA expression and signaling in breast cancer cells.

Performance Comment

RHOA was one of numerous potential early detection biomarkers specific to triple-negative breast cancer in multiple pathways identified.

Studies

This biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact Heather Kincaid at heather.kincaid@jpl.nasa.gov if you should have access to this biomarker.

Announcement 10/07/2014

EDRN Patient Advocates will host an EDRN Advocacy Educational Webinar, Biomarkers for Prostate Cancer Detection and Monitoring, on Monday, January 12th, 2015, at 1 p.m. EDT / 10 a.m. PDT. Registration is not required for this. Please click for more information.
Announcement 09/14/2014

Thank you to everyone who helped make the 9th EDRN Scientific Workshop a success. We look forward to seeing everyone at the 28th EDRN Steering Committee Meeting from March 31-April 2, 2015, in Atlanta, GA.