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PTPRE

Basics

Aliases:
This biomarker is also known as:
  • R-PTP-EPSILON,
  • receptor-type tyrosine-protein phosphatase epsilon,
  • protein tyrosine phosphatase, receptor type, epsilon polypeptide,
  • HPTPE,
  • R-PTP-epsilon,
  • EC 3.1.3.48,
  • PTPE,
  • protein tyrosine phosphatase, receptor type, E,
  • Protein-tyrosine phosphatase epsilon,

View in BioMuta

Description…

PTPRE is a member of the protein tyrosine phosphatase (PTP) family. Members of the PTP family are signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitosis, and oncogenic transformation. The PTPRE gene encodes two isoforms, one of which is a receptor-type PTP, and the other which is not a receptor-type PTP. Both isoforms act as negative regulators of FceRI-mediated signal transduction leading to cytokine production and degranulation.

Attributes

QA State: Curated
Type: Protein
Short Name:
HGNC Name: PTPRE

Datasets

There are no datasets associated with this biomarker.

Organs

The following organs have data associated with this biomarker…

Breast

Attributes

Phase: Two
QA State: Under Review

Overview

No additional breast data available.

Performance Comment

PTPRE was one of numerous potential early detection biomarkers specific to triple-negative breast cancer in multiple pathways identified.

Studies

This biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact Heather Kincaid at heather.kincaid@jpl.nasa.gov if you should have access to this biomarker.

2015 Steering Committee Meeting

The next EDRN Steering Committee Meeting will take place March 31st through April 2nd, 2015, in Atlanta, Georgia.

Announcement 02/12/2015

Please register for the 29th EDRN Steering Committee Meeting in Atlanta, GA from March 31-April 2, 2015. The registration page has information about booking hotel rooms and a draft agenda of the meeting.

Announcement