Aliases:This biomarker is also known as:
- protein tyrosine phosphatase, receptor type, c polypeptide,
- EC 22.214.171.124,
- Leukocyte common antigen,
- T200 glycoprotein,
- T200 leukocyte common antigen,
- receptor-type tyrosine-protein phosphatase C,
- CD45 antigen,
- protein tyrosine phosphatase, receptor type, C,
PTPRC is a member of the protein tyrosine phosphatase (PTP) family. Members of the PTP family are signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitosis, and oncogenic transformation. PTPRC is required for T-cell activation through the antigen receptor. PTPRC contains an extracellular domain, a single transmembrane segment and two tandem intracytoplasmic catalytic domains, and is classified as a receptor type PTP.
There are no datasets associated with this biomarker.
The following organs have data associated with this biomarker…
|QA State:||Under Review|
No additional breast data available.
PTPRC was one of numerous potential early detection biomarkers specific to triple-negative breast cancer in multiple pathways identified.