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PTPRC

Basics

Aliases:
This biomarker is also known as:
  • protein tyrosine phosphatase, receptor type, c polypeptide,
  • EC 3.1.3.48,
  • Leukocyte common antigen,
  • T200,
  • CD45R,
  • GP180,
  • LY5,
  • T200 glycoprotein,
  • T200 leukocyte common antigen,
  • receptor-type tyrosine-protein phosphatase C,
  • CD45,
  • L-CA,
  • CD45 antigen,
  • LCA,
  • B220,
  • protein tyrosine phosphatase, receptor type, C,

View in BioMuta

Description…

PTPRC is a member of the protein tyrosine phosphatase (PTP) family. Members of the PTP family are signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitosis, and oncogenic transformation. PTPRC is required for T-cell activation through the antigen receptor. PTPRC contains an extracellular domain, a single transmembrane segment and two tandem intracytoplasmic catalytic domains, and is classified as a receptor type PTP.

Attributes

QA State: Curated
Type: Protein
Short Name:
HGNC Name: PTPRC

Datasets

There are no datasets associated with this biomarker.

Organs

The following organs have data associated with this biomarker…

Breast

Attributes

Phase: Two
QA State: Under Review

Overview

No additional breast data available.

Performance Comment

PTPRC was one of numerous potential early detection biomarkers specific to triple-negative breast cancer in multiple pathways identified.

Studies

This biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact Heather Kincaid at heather.kincaid@jpl.nasa.gov if you should have access to this biomarker.

2015 EDRN PI Orientation

The New and Continuing EDRN Principal Investigator Orientation will take place October 15–16, 2015 in Bethesda, Maryland.

Announcement 06/30/2015

A funding opportunity for a new pancreatic cancer initiative, called The Pancreatic Cancer Detection Consortium (U01), has been released. For more information, please go to http://grants.nih.gov /grants/guide/ pa-files/ PAR-15-289.html.

Announcement 04/08/2015

Thank you to everyone who made the 29th EDRN Steering Committee Meeting a success. The orientation for new and continuing EDRN PIs will be held October 15-16, 2015 on the NCI campus. More information will be available later this summer.