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PRMT1

Basics

Aliases:
This biomarker is also known as:
  • HMT1 (hnRNP methyltransferase, S. cerevisiae)-like 2,
  • IR1B4,
  • Interferon receptor 1-bound protein 4,
  • Protein arginine N-methyltransferase 1,
  • ANM1,
  • HMT2,
  • HMT1 hnRNP methyltransferase-like 2 (S. cerevisiae),
  • HCP1,
  • Histone-arginine N-methyltransferase PRMT1,
  • HRMT1L2,

View in BioMuta

Description…

PRMT1 is an arginine N-methyltransferase that functions as a histone methyltransferase specific for H4. Together with dimethylated PIAS1, it represses STAT1 transcriptional activity, in the late phase of interferon gamma (IFN-gamma) signaling. PRMT1 may also be involved in the regulation of TAF15 transcriptional activity, act as an activator of estrogen receptor (ER)-mediated transactivation, play a key role in neurite outgrowth and act as a negative regulator of megakaryocytic differentiation, by modulating p38 MAPK pathway.PRMT1 is widely expressed.

Attributes

QA State: Under Review
Type: Protein
Short Name:
HGNC Name: PRMT1

Datasets

There are no datasets associated with this biomarker.

Organs

This biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact Heather Kincaid at heather.kincaid@jpl.nasa.gov if you should have access to this biomarker.

Studies

This biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact Heather Kincaid at heather.kincaid@jpl.nasa.gov if you should have access to this biomarker.

Publications

This biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact Heather Kincaid at heather.kincaid@jpl.nasa.gov if you should have access to this biomarker.

Resources

This biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact Heather Kincaid at heather.kincaid@jpl.nasa.gov if you should have access to this biomarker.

2015 Steering Committee Meeting

The next EDRN Steering Committee Meeting will take place March 31st through April 2nd, 2015, in Atlanta, Georgia.

Announcement 02/12/2015

Please register for the 29th EDRN Steering Committee Meeting in Atlanta, GA from March 31-April 2, 2015. The registration page has information about booking hotel rooms and a draft agenda of the meeting.

Announcement