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POSTN

Basics

Aliases:
This biomarker is also known as:
  • periostin,
  • periostin, osteoblast specific factor,
  • PN,
  • OSF-2,
  • Osteoblast-specific factor 2,
  • OSF2,

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Description…

POSTN, a secreted protein, binds to heparin and induces cell attachment and spreading. It may additionally play a role in cell adhesion and in extracellular matrix mineralization. POSTN is widely expressed with highest levels in aorta, stomach, lower gastrointestinal tract, placenta, uterus and breast. It is up-regulated in epithelial ovarian tumors while not expressed in normal ovaries. POSTN is also highly expressed at the tumor periphery of lung carcinoma tissue but not within the tumor. It is overexpressed in breast cancers.

Attributes

QA State: Under Review
Type: Protein
Short Name:
HGNC Name: POSTN

Datasets

There are no datasets associated with this biomarker.

Organs

This biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact Heather Kincaid at heather.kincaid@jpl.nasa.gov if you should have access to this biomarker.

Studies

This biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact Heather Kincaid at heather.kincaid@jpl.nasa.gov if you should have access to this biomarker.

Publications

This biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact Heather Kincaid at heather.kincaid@jpl.nasa.gov if you should have access to this biomarker.

Resources

This biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact Heather Kincaid at heather.kincaid@jpl.nasa.gov if you should have access to this biomarker.

2015 EDRN PI Orientation

The New and Continuing EDRN Principal Investigator Orientation will take place October 15–16, 2015 in Bethesda, Maryland.

Announcement 04/08/2015

Thank you to everyone who made the 29th EDRN Steering Committee Meeting a success. The orientation for new and continuing EDRN PIs will be held October 15-16, 2015 on the NCI campus. More information will be available later this summer.

Announcement