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PCCA

Basics

Aliases:
This biomarker is also known as:
  • propionyl CoA carboxylase, alpha polypeptide,
  • EC 6.4.1.3,
  • Propanoyl-CoA:carbon dioxide ligase subunit alpha,
  • propionyl-CoA carboxylase alpha chain, mitochondrial,
  • pccA complementation group,
  • propionyl Coenzyme A carboxylase, alpha polypeptide,
  • PCCase alpha subunit,
  • propanoyl-CoA:carbon dioxide ligase alpha subunit,
  • PCCase subunit alpha,

View in BioMuta

Description…

PCCA, or propionyl CoA carboxylase, alpha polypeptide, is the alpha subunit of the heterodimeric mitochondrial enzyme Propionyl-CoA carboxylase. The beta subunit is PCCB. The enzyme deficiency propionic acidemia results from mutations in either PCCA or PCCB. Several isoforms for this gene have been identified, coded by multiple transcript variants.

Attributes

QA State: Curated
Type: Protein
Short Name:
HGNC Name: PCCA

Datasets

There are no datasets associated with this biomarker.

Organs

The following organs have data associated with this biomarker…

Breast

Attributes

Phase: Two
QA State: Under Review

Overview

No additional breast data available.

Performance Comment

PCCA was one of numerous potential early detection biomarkers specific to triple-negative breast cancer in multiple pathways identified.

Studies

This biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact Heather Kincaid at heather.kincaid@jpl.nasa.gov if you should have access to this biomarker.

2015 Steering Committee Meeting

The next EDRN Steering Committee Meeting will take place March 31st through April 2nd, 2015, in Atlanta, Georgia.

Announcement 02/12/2015

Please register for the 29th EDRN Steering Committee Meeting in Atlanta, GA from March 31-April 2, 2015. The registration page has information about booking hotel rooms and a draft agenda of the meeting.

Announcement