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PCCA

Basics

Aliases:
This biomarker is also known as:
  • propanoyl-CoA:carbon dioxide ligase alpha subunit,
  • PCCase alpha subunit,
  • Propanoyl-CoA:carbon dioxide ligase subunit alpha,
  • propionyl-CoA carboxylase alpha chain, mitochondrial,
  • EC 6.4.1.3,
  • pccA complementation group,
  • propionyl Coenzyme A carboxylase, alpha polypeptide,
  • PCCase subunit alpha,
  • propionyl CoA carboxylase, alpha polypeptide,

View in BioMuta

Description…

PCCA, or propionyl CoA carboxylase, alpha polypeptide, is the alpha subunit of the heterodimeric mitochondrial enzyme Propionyl-CoA carboxylase. The beta subunit is PCCB. The enzyme deficiency propionic acidemia results from mutations in either PCCA or PCCB. Several isoforms for this gene have been identified, coded by multiple transcript variants.

Attributes

QA State: Curated
Type: Protein
Short Name:
HGNC Name: PCCA

Datasets

There are no datasets associated with this biomarker.

Organs

The following organs have data associated with this biomarker…

Breast

Attributes

Phase: Two
QA State: Under Review

Overview

No additional breast data available.

Performance Comment

PCCA was one of numerous potential early detection biomarkers specific to triple-negative breast cancer in multiple pathways identified.

Studies

This biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact Heather Kincaid at heather.kincaid@jpl.nasa.gov if you should have access to this biomarker.

Announcement 10/07/2014

EDRN Patient Advocates will host an EDRN Advocacy Educational Webinar, Biomarkers for Prostate Cancer Detection and Monitoring, on Monday, January 12th, 2015, at 1 p.m. EDT / 10 a.m. PDT. Registration is not required for this. Please click for more information.
Announcement 09/14/2014

Thank you to everyone who helped make the 9th EDRN Scientific Workshop a success. We look forward to seeing everyone at the 28th EDRN Steering Committee Meeting from March 31-April 2, 2015, in Atlanta, GA.