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NOS1

Basics

Aliases:
This biomarker is also known as:
  • NOS,
  • N-NOS,
  • bNOS,
  • nitric oxide synthase, brain,
  • Neuronal NOS,
  • Constitutive NOS,
  • peptidyl-cysteine S-nitrosylase NOS1,
  • nitric oxide synthase 1 (neuronal),
  • NC-NOS,
  • nNOS,
  • NOS type I,
  • IHPS1,
  • EC 1.14.13.39,
  • constitutive NOS,
  • Peptidyl-cysteine S-nitrosylase NOS1,
  • neuronal NOS,

View in BioMuta

Description…

NOS1, or nitric oxide synthase 1 (neuronal), along with inducible nitric oxide synthase (NOS2) and endothelial nitric oxide synthase (NOS3), catalyze the generation of nitric oxide and L-citrulline from L-arginine and molecular oxygen. Nitric oxide is a messenger molecule with diverse functions throughout the body. In the brain and peripheral nervous system, nitric oxide displays many properties of a neurotransmitter. NOS1 also displays antimicrobial and antitumoral activities.

Attributes

QA State: Curated
Type: Protein
Short Name:
HGNC Name: NOS1

Datasets

There are no datasets associated with this biomarker.

Organs

The following organs have data associated with this biomarker…

Breast

Attributes

Phase: Two
QA State: Under Review

Overview

No additional breast data available.

Performance Comment

NOS1 was one of numerous potential early detection biomarkers specific to triple-negative breast cancer in multiple pathways identified.

Studies

This biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact Heather Kincaid at heather.kincaid@jpl.nasa.gov if you should have access to this biomarker.

Announcement 10/07/2014

EDRN Patient Advocates will host an EDRN Advocacy Educational Webinar, Biomarkers for Prostate Cancer Detection and Monitoring, on Monday, January 12th, 2015, at 1 p.m. EDT / 10 a.m. PDT. Registration is not required for this. Please click for more information.
Announcement 09/14/2014

Thank you to everyone who helped make the 9th EDRN Scientific Workshop a success. We look forward to seeing everyone at the 28th EDRN Steering Committee Meeting from March 31-April 2, 2015, in Atlanta, GA.