Skip to content. | Skip to navigation

National Cancer Institute U.S. National Institutes of Health www.cancer.gov

Navigation

Personal tools

You are here: Home / Biomarkers / NDUFA10

NDUFA10

Basics

Aliases:
This biomarker is also known as:
  • NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 10 (42kD),
  • NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 10, 42kDa,
  • CI-42kD,
  • NADH-ubiquinone oxidoreductase 42 kDa subunit,
  • complex I 42kDa subunit,
  • Complex I-42kD,
  • NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial,
  • CI-42KD,
  • CI-42k,

View in BioMuta

Description…

NDUFA10 is an accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Mammalian complex I is the first enzyme complex in the electron transport chain of mitochondria. It is composed of 45 different subunits. This protein is a component of the hydrophobic protein fraction and has NADH dehydrogenase activity and oxidoreductase activity. It transfers electrons from NADH to the respiratory chain.

Attributes

QA State: Curated
Type: Protein
Short Name:
HGNC Name: NDUFA10

Datasets

There are no datasets associated with this biomarker.

Organs

The following organs have data associated with this biomarker…

Breast

Attributes

Phase: Two
QA State: Under Review

Overview

No additional breast data available.

Performance Comment

NDUFA10 was one of numerous potential early detection biomarkers specific to triple-negative breast cancer in multiple pathways identified.

Studies

This biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact Heather Kincaid at heather.kincaid@jpl.nasa.gov if you should have access to this biomarker.

Announcement 10/07/2014

EDRN Patient Advocates will host an EDRN Advocacy Educational Webinar, Biomarkers for Prostate Cancer Detection and Monitoring, on Monday, January 12th, 2015, at 1 p.m. EDT / 10 a.m. PDT. Registration is not required for this. Please click for more information.
Announcement 09/14/2014

Thank you to everyone who helped make the 9th EDRN Scientific Workshop a success. We look forward to seeing everyone at the 28th EDRN Steering Committee Meeting from March 31-April 2, 2015, in Atlanta, GA.