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LPAR3

Basics

Aliases:
This biomarker is also known as:
  • RP4-678I3,
  • endothelial differentiation, lysophosphatidic acid G-protein-coupled receptor, 7,
  • EDG7,
  • LPA3,
  • LP-A3,
  • GPCR,
  • LPA receptor 3,
  • Edg-7,
  • HOFNH30,
  • LPA-3,
  • FLJ98231,
  • lysophosphatidic acid receptor 3,

View in BioMuta

Description…

LPAR3, a multi-pass cell membrane protein, is a receptor for lysophosphatidic acid (LPA), a mediator of diverse cellular activities. LPAR3 seems to be coupled to the G(i)/G(o) and G(q) families of heteromeric G proteins. LPAR3 may play a role in the development of ovarian cancer. This protein is most abundantly expressed in prostate, testes, pancreas, and heart, with moderate levels in lung and ovary. There is no detectable expression in brain, placenta, liver, skeletal muscle, kidney, spleen, thymus, small intestine, colon, or peripheral blood leukocytes.

Attributes

QA State: Under Review
Type: Protein
Short Name:
HGNC Name: LPAR3

Datasets

There are no datasets associated with this biomarker.

Organs

This biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact Heather Kincaid at heather.kincaid@jpl.nasa.gov if you should have access to this biomarker.

Studies

This biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact Heather Kincaid at heather.kincaid@jpl.nasa.gov if you should have access to this biomarker.

Publications

This biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact Heather Kincaid at heather.kincaid@jpl.nasa.gov if you should have access to this biomarker.

Resources

This biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact Heather Kincaid at heather.kincaid@jpl.nasa.gov if you should have access to this biomarker.

Announcement 11/20/2014

New Round of EDRN FOAs

The RFAs for EDRN have been released:
- Biomarker Developmental Laboratories (U01),
- Clinical Validation Centers (U01),
- Biomarker Reference Laboratories (U24),
- Data Management and Coordinating Center (U24).

EDRN Renewal flyer NOTE-New receipt deadline for applications submitted for all EDRN FOAs is January 20, 2015, by 5:00 PM local time of applicant organization.

There will be a Pre-Application webinar to discuss each of the four individual EDRN FOAs on Tuesday, December 2nd, 2014, from 1pm-5pm (Eastern). Potential applicants interested in participating in the webinar should send a message to Dr. Sharmistha Ghosh (ghoshjanjigias@mail.nih.gov) no later than 5:00 p.m. (EST) November 21, 2014. Please mention the FOA of interest in the subject line.

Announcement 10/07/2014

EDRN Patient Advocates will host an EDRN Advocacy Educational Webinar, Biomarkers for Prostate Cancer Detection and Monitoring, on Monday, January 12th, 2015, at 1 p.m. EDT / 10 a.m. PDT. Registration is not required for this. Please click for more information.