Aliases:This biomarker is also known as:
- lysophosphatidic acid receptor 3,
- endothelial differentiation, lysophosphatidic acid G-protein-coupled receptor, 7,
- LPA receptor 3,
LPAR3, a multi-pass cell membrane protein, is a receptor for lysophosphatidic acid (LPA), a mediator of diverse cellular activities. LPAR3 seems to be coupled to the G(i)/G(o) and G(q) families of heteromeric G proteins. LPAR3 may play a role in the development of ovarian cancer. This protein is most abundantly expressed in prostate, testes, pancreas, and heart, with moderate levels in lung and ovary. There is no detectable expression in brain, placenta, liver, skeletal muscle, kidney, spleen, thymus, small intestine, colon, or peripheral blood leukocytes.
|QA State:||Under Review|
There are no datasets associated with this biomarker.