Skip to content. | Skip to navigation

National Cancer Institute U.S. National Institutes of Health


Personal tools

You are here: Home / Biomarkers / LGALS3BP



This biomarker is also known as:
  • serum protein 90K,
  • MAC-2-BP,
  • BTBD17B,
  • lectin, galactoside-binding, soluble, 3 binding protein,
  • Mac-2 BP,
  • Tumor-associated antigen 90K,
  • mac-2 BP,
  • L3 antigen,
  • tumor-associated antigen 90K,
  • basement membrane autoantigen p105,
  • Lectin galactoside-binding soluble 3-binding protein,
  • Mac-2-binding protein,
  • galectin-3-binding protein,
  • MAC2BP,
  • Basement membrane autoantigen p105,
  • M2BP,
  • Q08380,
  • 90K,
  • lectin galactoside-binding soluble 3-binding protein,

View in BioMuta


LGALS3BP is a secreted protein that binds to a human macrophage-associated lectin known as Mac-2 and also binds galectin 1. Elevated levels of LGALS3BP have been found in the serum of patients with cancer and in those infected by the human immunodeficiency virus (HIV).


QA State: Curated
Type: Protein
Short Name:


There are no datasets associated with this biomarker.


The following organs have data associated with this biomarker…



Phase: One
QA State: Under Review


Average expression of LGALS3BP was significantly higher in epithelial ovarian cancer tumors than any other normal tissue tested.

Performance Comment

LGALS3BP was one of 13 genes out of 50 selected for further validation in PMID:21617380.


This biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact Heather Kincaid at if you should have access to this biomarker.

2016 EDRN PI Orientation

The New and Continuing EDRN Principal Investigator Orientation will take place March 14–15, 2016 in Bethesda, Maryland.

Announcement 11/05/2015

Thank you to everyone who made the 29th EDRN Steering Committee Meeting a success. The orientation for new and continuing EDRN PIs will be held Monday-Tuesday, March 14-15, 2016, on the NCI campus. More information will be available later this autumn.

Announcement 06/30/2015

A funding opportunity for a new pancreatic cancer initiative, called The Pancreatic Cancer Detection Consortium (U01), has been released. For more information, please go to /grants/guide/ pa-files/ PAR-15-289.html.