Skip to content. | Skip to navigation

National Cancer Institute U.S. National Institutes of Health www.cancer.gov

Navigation

Personal tools

You are here: Home / Biomarkers / LGALS3BP

LGALS3BP

Basics

Aliases:
This biomarker is also known as:
  • Mac-2 BP,
  • lectin galactoside-binding soluble 3-binding protein,
  • serum protein 90K,
  • galectin-3-binding protein,
  • Mac-2-binding protein,
  • 90K,
  • MAC2BP,
  • mac-2 BP,
  • Basement membrane autoantigen p105,
  • Lectin galactoside-binding soluble 3-binding protein,
  • M2BP,
  • Tumor-associated antigen 90K,
  • MAC-2-BP,
  • L3 antigen,
  • Q08380,
  • basement membrane autoantigen p105,
  • tumor-associated antigen 90K,
  • lectin, galactoside-binding, soluble, 3 binding protein,
  • BTBD17B,

View in BioMuta

Description…

LGALS3BP is a secreted protein that binds to a human macrophage-associated lectin known as Mac-2 and also binds galectin 1. Elevated levels of LGALS3BP have been found in the serum of patients with cancer and in those infected by the human immunodeficiency virus (HIV).

Attributes

QA State: Curated
Type: Protein
Short Name:
HGNC Name: LGALS3BP

Datasets

There are no datasets associated with this biomarker.

Organs

The following organs have data associated with this biomarker…

Ovary

Attributes

Phase: One
QA State: Under Review

Overview

Average expression of LGALS3BP was significantly higher in epithelial ovarian cancer tumors than any other normal tissue tested.

Performance Comment

LGALS3BP was one of 13 genes out of 50 selected for further validation in PMID:21617380.

Studies

This biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact Heather Kincaid at heather.kincaid@jpl.nasa.gov if you should have access to this biomarker.

Announcement 11/20/2014

New Round of EDRN FOAs

The RFAs for EDRN have been released:
- Biomarker Developmental Laboratories (U01),
- Clinical Validation Centers (U01),
- Biomarker Reference Laboratories (U24),
- Data Management and Coordinating Center (U24).

EDRN Renewal flyer NOTE-New receipt deadline for applications submitted for all EDRN FOAs is January 20, 2015, by 5:00 PM local time of applicant organization.

There will be a Pre-Application webinar to discuss each of the four individual EDRN FOAs on Tuesday, December 2nd, 2014, from 1pm-5pm (Eastern). Potential applicants interested in participating in the webinar should send a message to Dr. Sharmistha Ghosh (ghoshjanjigias@mail.nih.gov) no later than 5:00 p.m. (EST) November 21, 2014. Please mention the FOA of interest in the subject line.

Announcement 10/07/2014

EDRN Patient Advocates will host an EDRN Advocacy Educational Webinar, Biomarkers for Prostate Cancer Detection and Monitoring, on Monday, January 12th, 2015, at 1 p.m. EDT / 10 a.m. PDT. Registration is not required for this. Please click for more information.