Skip to content. | Skip to navigation

National Cancer Institute U.S. National Institutes of Health www.cancer.gov

Navigation

Personal tools

You are here: Home / Biomarkers / LGALS3BP

LGALS3BP

Basics

Aliases:
This biomarker is also known as:
  • basement membrane autoantigen p105,
  • Mac-2 BP,
  • MAC-2-BP,
  • M2BP,
  • Mac-2-binding protein,
  • serum protein 90K,
  • MAC2BP,
  • BTBD17B,
  • Lectin galactoside-binding soluble 3-binding protein,
  • mac-2 BP,
  • Tumor-associated antigen 90K,
  • L3 antigen,
  • galectin-3-binding protein,
  • tumor-associated antigen 90K,
  • Basement membrane autoantigen p105,
  • Q08380,
  • lectin galactoside-binding soluble 3-binding protein,
  • lectin, galactoside-binding, soluble, 3 binding protein,
  • 90K,

View in BioMuta

Description…

LGALS3BP is a secreted protein that binds to a human macrophage-associated lectin known as Mac-2 and also binds galectin 1. Elevated levels of LGALS3BP have been found in the serum of patients with cancer and in those infected by the human immunodeficiency virus (HIV).

Attributes

QA State: Curated
Type: Protein
Short Name:
HGNC Name: LGALS3BP

Datasets

There are no datasets associated with this biomarker.

Organs

The following organs have data associated with this biomarker…

Ovary

Attributes

Phase: One
QA State: Under Review

Overview

Average expression of LGALS3BP was significantly higher in epithelial ovarian cancer tumors than any other normal tissue tested.

Performance Comment

LGALS3BP was one of 13 genes out of 50 selected for further validation in PMID:21617380.

Studies

This biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact Heather Kincaid at heather.kincaid@jpl.nasa.gov if you should have access to this biomarker.

2015 EDRN PI Orientation

The New and Continuing EDRN Principal Investigator Orientation will take place October 15–16, 2015 in Bethesda, Maryland.

Announcement 06/30/2015

A funding opportunity for a new pancreatic cancer initiative, called The Pancreatic Cancer Detection Consortium (U01), has been released. For more information, please go to http://grants.nih.gov /grants/guide/ pa-files/ PAR-15-289.html.

Announcement 04/08/2015

Thank you to everyone who made the 29th EDRN Steering Committee Meeting a success. The orientation for new and continuing EDRN PIs will be held October 15-16, 2015 on the NCI campus. More information will be available later this summer.