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This biomarker is also known as:
  • lymphocyte cytosolic protein 2 (SH2 domain-containing leukocyte protein of 76kD),
  • SLP-76 tyrosine phosphoprotein,
  • SLP-76,
  • lymphocyte cytosolic protein 2,
  • SH2 domain-containing leukocyte protein of 76 kDa,
  • lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa),
  • 76 kDa tyrosine phosphoprotein,
  • SH2 domain-containing leukocyte protein of 76kD,
  • SLP76,

View in BioMuta


LCP2, previously known as SLP76, functions as an adaptor or scaffolding protein. LCP2 has three modular domains. The amino-terminal end has an acidic region that includes a PEST domain and several tyrosine residues which are phosphorylated following TCR ligation. LCP2 also contains a central proline-rich domain and a COOH-terminal SH2 domain.


QA State: Curated
Type: Protein
Short Name:


There are no datasets associated with this biomarker.


The following organs have data associated with this biomarker…



Phase: Two
QA State: Under Review


No additional breast data is available.

Performance Comment

LCP2 was one of numerous potential early detection biomarkers specific to triple-negative breast cancer in multiple pathways identified.


This biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact Heather Kincaid at if you should have access to this biomarker.

2016 EDRN PI Orientation

The New and Continuing EDRN Principal Investigator Orientation will take place March 14–15, 2016 in Bethesda, Maryland.

Announcement 11/05/2015

Thank you to everyone who made the 29th EDRN Steering Committee Meeting a success. The orientation for new and continuing EDRN PIs will be held Monday-Tuesday, March 14-15, 2016, on the NCI campus. More information will be available later this autumn.

Announcement 06/30/2015

A funding opportunity for a new pancreatic cancer initiative, called The Pancreatic Cancer Detection Consortium (U01), has been released. For more information, please go to /grants/guide/ pa-files/ PAR-15-289.html.