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KRAS

Basics

Aliases:
This biomarker is also known as:
  • K-RAS2B,
  • RASK2,
  • PR310 c-K-ras oncogene,
  • K-RAS4A,
  • cellular c-Ki-ras2 proto-oncogene,
  • KRAS2,
  • NS,
  • K-RAS4B,
  • c-Kirsten-ras protein,
  • K-RAS2A,
  • NS3,
  • v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog,
  • KRAS1,
  • C-K-RAS,
  • KI-RAS,
  • K-ras p21 protein,
  • oncogene KRAS2,
  • c-K-ras2 protein,
  • transforming protein p21,
  • Kirsten rat sarcoma-2 viral (v-Ki-ras2) oncogene homolog,

View in BioMuta

Description…

The KRAS gene, a Kirsten ras oncogene homolog from the mammalian ras gene family, encodes a protein that is a member of the small GTPase superfamily. A single amino acid substitution is responsible for an activating mutation. The transforming protein that results is implicated in various malignancies, including lung adenocarcinoma, mucinous adenoma, ductal carcinoma of the pancreas and colorectal carcinoma. Alternative splicing leads to variants encoding two isoforms that differ in the C-terminal region.

Attributes

QA State: Under Review
Type: Protein
Short Name:
HGNC Name: KRAS

Datasets

There are no datasets associated with this biomarker.

Organs

This biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact Heather Kincaid at heather.kincaid@jpl.nasa.gov if you should have access to this biomarker.

Studies

This biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact Heather Kincaid at heather.kincaid@jpl.nasa.gov if you should have access to this biomarker.

Publications

This biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact Heather Kincaid at heather.kincaid@jpl.nasa.gov if you should have access to this biomarker.

Resources

This biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact Heather Kincaid at heather.kincaid@jpl.nasa.gov if you should have access to this biomarker.

2015 EDRN PI Orientation

The New and Continuing EDRN Principal Investigator Orientation will take place October 15–16, 2015 in Bethesda, Maryland.

Announcement 04/08/2015

Thank you to everyone who made the 29th EDRN Steering Committee Meeting a success. The orientation for new and continuing EDRN PIs will be held October 15-16, 2015 on the NCI campus. More information will be available later this summer.

Announcement