Skip to content. | Skip to navigation

National Cancer Institute U.S. National Institutes of Health www.cancer.gov

Navigation

Personal tools

You are here: Home / Biomarkers / KRAS

KRAS

Basics

Aliases:
This biomarker is also known as:
  • cellular c-Ki-ras2 proto-oncogene,
  • c-K-ras2 protein,
  • v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog,
  • C-K-RAS,
  • c-Kirsten-ras protein,
  • oncogene KRAS2,
  • NS3,
  • K-RAS4B,
  • NS,
  • K-RAS2A,
  • K-ras p21 protein,
  • KI-RAS,
  • KRAS2,
  • transforming protein p21,
  • Kirsten rat sarcoma-2 viral (v-Ki-ras2) oncogene homolog,
  • K-RAS2B,
  • RASK2,
  • PR310 c-K-ras oncogene,
  • KRAS1,
  • K-RAS4A,

View in BioMuta

Description…

The KRAS gene, a Kirsten ras oncogene homolog from the mammalian ras gene family, encodes a protein that is a member of the small GTPase superfamily. A single amino acid substitution is responsible for an activating mutation. The transforming protein that results is implicated in various malignancies, including lung adenocarcinoma, mucinous adenoma, ductal carcinoma of the pancreas and colorectal carcinoma. Alternative splicing leads to variants encoding two isoforms that differ in the C-terminal region.

Attributes

QA State: Under Review
Type: Protein
Short Name:
HGNC Name: KRAS

Datasets

There are no datasets associated with this biomarker.

Organs

This biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact Heather Kincaid at heather.kincaid@jpl.nasa.gov if you should have access to this biomarker.

Studies

This biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact Heather Kincaid at heather.kincaid@jpl.nasa.gov if you should have access to this biomarker.

Publications

This biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact Heather Kincaid at heather.kincaid@jpl.nasa.gov if you should have access to this biomarker.

Resources

This biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact Heather Kincaid at heather.kincaid@jpl.nasa.gov if you should have access to this biomarker.

Announcement 10/07/2014

EDRN Patient Advocates will host an EDRN Advocacy Educational Webinar, Biomarkers for Prostate Cancer Detection and Monitoring, on Monday, January 12th, 2015, at 1 p.m. EDT / 10 a.m. PDT. Registration is not required for this. Please click for more information.
Announcement 09/14/2014

Thank you to everyone who helped make the 9th EDRN Scientific Workshop a success. We look forward to seeing everyone at the 28th EDRN Steering Committee Meeting from March 31-April 2, 2015, in Atlanta, GA.