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KCNH5

Basics

Aliases:
This biomarker is also known as:
  • ether-a-go-go-related potassium channel 2,
  • potassium channel HEAG2,
  • hEAG2,
  • voltage-gated potassium channel EAG2,
  • Voltage-gated potassium channel subunit Kv10.2,
  • eag2,
  • Ether-a-go-go potassium channel 2,
  • H-EAG2,
  • potassium voltage-gated channel subfamily H member 5,
  • potassium voltage-gated channel, subfamily H (eag-related), member 5,
  • EAG2,
  • Kv10.2,

View in BioMuta

Description…

KCNH5 is a member of the potassium channel, voltage-gated, subfamily H family of voltage-gated potassium channels. The voltage-gated potassium channels are a complex class, both functionally and structurally. Functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. This member, KCNH5, is a pore-forming (alpha) subunit of a voltage-gated non-inactivating delayed rectifier potassium channel. The pore-forming alpha-subunits contain a single pore-forming region and combine to form tetramers. Alternative splicing results in three transcript variants encoding distinct isoforms.

Attributes

QA State: Under Review
Type: Gene
Short Name:
HGNC Name: KCNH5

Datasets

There are no datasets associated with this biomarker.

Organs

This biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact Heather Kincaid at heather.kincaid@jpl.nasa.gov if you should have access to this biomarker.

Studies

This biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact Heather Kincaid at heather.kincaid@jpl.nasa.gov if you should have access to this biomarker.

Publications

This biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact Heather Kincaid at heather.kincaid@jpl.nasa.gov if you should have access to this biomarker.

Resources

This biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact Heather Kincaid at heather.kincaid@jpl.nasa.gov if you should have access to this biomarker.

2015 Steering Committee Meeting

The next EDRN Steering Committee Meeting will take place March 31st through April 2nd, 2015, in Atlanta, Georgia.

Announcement 12/02/2014

New Round of EDRN FOAs

The RFAs for EDRN have been released:
- Biomarker Developmental Laboratories (U01),
- Clinical Validation Centers (U01),
- Biomarker Reference Laboratories (U24),
- Data Management and Coordinating Center (U24).

EDRN Renewal flyer NOTE-New receipt deadline for applications submitted for all EDRN FOAs is January 20, 2015, by 5:00 PM local time of applicant organization.

There will be a Pre-Application webinar to discuss each of the four individual EDRN FOAs on Tuesday, December 2nd, 2014, from 1pm-5pm (Eastern). Potential applicants interested in participating in the webinar should send a message to Dr. Sharmistha Ghosh (ghoshjanjigias@mail.nih.gov) no later than 5:00 p.m. (EST) November 21, 2014. Please mention the FOA of interest in the subject line.

Announcement 10/07/2014

EDRN Patient Advocates will host an EDRN Advocacy Educational Webinar, Biomarkers for Prostate Cancer Detection and Monitoring, on Monday, January 12th, 2015, at 1 p.m. EDT / 10 a.m. PDT. Registration is not required for this. Please click for more information.