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IMPDH2

Basics

Aliases:
This biomarker is also known as:
  • IMPDH-II,
  • inosine-5'-monophosphate dehydrogenase 2,
  • IMP (inosine 5'-monophosphate) dehydrogenase 2,
  • inosine 5' phosphate dehydrogenase 2,
  • IMPDH 2,
  • IMPD2,
  • IMPDH,
  • IMP (inosine monophosphate) dehydrogenase 2,
  • IMP dehydrogenase 2,
  • IMP oxireductase 2,
  • IMPD 2,
  • inosine monophosphate dehydrogenase type II,
  • EC 1.1.1.205,

View in BioMuta

Description…

The enzyme IMPDH2 catalyzes the rate-limiting step of conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed step in the de novo synthesis of guanine nucleotides. Therefore IMPDH2 is involved in maintaining cellular guanine deoxy- and ribonucleotide pools needed for DNA and RNA synthesis. It is also thought to be involvedmin the development of malignancy and the growth progression of some tumors.

Attributes

QA State: Under Review
Type: Protein
Short Name:
HGNC Name: IMPDH2

Datasets

There are no datasets associated with this biomarker.

Organs

This biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact Heather Kincaid at heather.kincaid@jpl.nasa.gov if you should have access to this biomarker.

Studies

This biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact Heather Kincaid at heather.kincaid@jpl.nasa.gov if you should have access to this biomarker.

Publications

This biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact Heather Kincaid at heather.kincaid@jpl.nasa.gov if you should have access to this biomarker.

Resources

This biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact Heather Kincaid at heather.kincaid@jpl.nasa.gov if you should have access to this biomarker.

2015 Steering Committee Meeting

The next EDRN Steering Committee Meeting will take place March 31st through April 2nd, 2015, in Atlanta, Georgia.

Announcement 02/12/2015

Please register for the 29th EDRN Steering Committee Meeting in Atlanta, GA from March 31-April 2, 2015. The registration page has information about booking hotel rooms and a draft agenda of the meeting.

Announcement