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IL10

Basics

Aliases:
This biomarker is also known as:
  • interleukin 10,
  • CSIF,
  • cytokine synthesis inhibitory factor,
  • IL-10,
  • TGIF,
  • IL10A,
  • Interleukin-10,
  • T-cell growth inhibitory factor,

View in BioMuta

Description…

Interleukin 10, a secreted protein belonging to the IL-10 family, is a cytokine produced primarily by monocytes and to a lesser extent by lymphocytes. It down-regulates the expression of cytokines IL-2, IL-3, TNF and GM-CSF produced by activated macrophages and by helper T-cells, MHC class II Ags, and costimulatory molecules on macrophages.

Attributes

QA State: Curated
Type: Protein
Short Name:
HGNC Name: IL10

Datasets

There are no datasets associated with this biomarker.

Organs

The following organs have data associated with this biomarker…

Ovary

Attributes

Phase: Two
QA State: Curated

Overview

IL10 alone was not a strong predictor of ovarian cancer.

Performance Comment

Despite many promising new markers for ovarian cancer, CA125 remains the single best biomarker in the phase II and phase III specimens tested in this study.

Studies

This biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact Heather Kincaid at heather.kincaid@jpl.nasa.gov if you should have access to this biomarker.

Announcement 10/07/2014

EDRN Patient Advocates will host an EDRN Advocacy Educational Webinar, Biomarkers for Prostate Cancer Detection and Monitoring, on Monday, January 12th, 2015, at 1 p.m. EDT / 10 a.m. PDT. Registration is not required for this. Please click for more information.
Announcement 09/14/2014

Thank you to everyone who helped make the 9th EDRN Scientific Workshop a success. We look forward to seeing everyone at the 28th EDRN Steering Committee Meeting from March 31-April 2, 2015, in Atlanta, GA.