Aliases:This biomarker is also known as:
- Type II HADH,
- short chain type dehydrogenase/reductase XH98G2,
- amyloid-beta peptide binding alcohol dehydrogenase,
- EC 184.108.40.206,EC 220.127.116.11,
- 3-hydroxy-2-methylbutyryl-CoA dehydrogenase,
- mental retardation, X-linked, syndromic 10,
- Mitochondrial ribonuclease P protein 2,
- hydroxyacyl-Coenzyme A dehydrogenase, type II, hydroxyacyl-Coenzyme A dehydrogenase, type II,
- mitochondrial RNase P subunit 2,
- Mitochondrial RNase P protein 2,
- hydroxysteroid (17-beta) dehydrogenase 10,
- 17-beta-HSD 10,
- 17-beta-hydroxysteroid dehydrogenase 10,
- Short-chain type dehydrogenase/reductase XH98G2,
- AB-binding alcohol dehydrogenase,
- mitochondrial ribonuclease P protein 2,
- endoplasmic reticulum-associated amyloid beta-peptide-binding protein,
- short chain L-3-hydroxyacyl-CoA dehydrogenase type 2,
- Endoplasmic reticulum-associated amyloid beta-peptide-binding protein,
- short chain dehydrogenase/reductase family 5C, member 1,
- 3-hydroxyacyl-CoA dehydrogenase type II,
- 3-hydroxyacyl-CoA dehydrogenase type-2,
HSD17B10, hydroxysteroid (17-beta) dehydrogenase 10, is a member of the short-chain dehydrogenase/reductase superfamily. HSD17B10 functions in mitochondrial tRNA maturation and catalyzes the oxidation of a wide variety of fatty acids, alcohols, and steroids. The protein is thought to play a role in the development of Alzheimer's disease. There are several alternatively spliced transcript variants, of which only two have been fully sequenced.
There are no datasets associated with this biomarker.
The following organs have data associated with this biomarker…
|QA State:||Under Review|
No additional breast data is available.
HSD17B10 was one of numerous potential early detection biomarkers specific to triple-negative breast cancer in multiple pathways identified.
- Discovery and preliminary confirmation of novel early detection biomarkers for triple-negative breast cancer using preclinical plasma samples from the Women's Health Initiative observational study.
- Plasma biomarker profiles differ depending on breast cancer subtype but RANTES is consistently increased.