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HSD17B10

Basics

Aliases:
This biomarker is also known as:
  • Type II HADH,
  • ABAD,
  • mitochondrial RNase P subunit 2,
  • 3-hydroxyacyl-CoA dehydrogenase type-2,
  • EC 1.1.1.35,EC 1.1.1.178,
  • XH98G2,
  • 17-beta-HSD 10,
  • Mitochondrial ribonuclease P protein 2,
  • HADH2,
  • MRPP2,
  • 17b-HSD10,
  • MRXS10,
  • SDR5C1,
  • 3-hydroxyacyl-CoA dehydrogenase type II,
  • mental retardation, X-linked, syndromic 10,
  • short chain dehydrogenase/reductase family 5C, member 1,
  • Endoplasmic reticulum-associated amyloid beta-peptide-binding protein,
  • 3-hydroxy-2-methylbutyryl-CoA dehydrogenase,
  • 17-beta-hydroxysteroid dehydrogenase 10,
  • AB-binding alcohol dehydrogenase,
  • MRX17,
  • endoplasmic reticulum-associated amyloid beta-peptide-binding protein,
  • DUPXp11.22,
  • hydroxysteroid (17-beta) dehydrogenase 10,
  • short chain type dehydrogenase/reductase XH98G2,
  • CAMR,
  • amyloid-beta peptide binding alcohol dehydrogenase,
  • ERAB,
  • short chain L-3-hydroxyacyl-CoA dehydrogenase type 2,
  • SCHAD,
  • MRX31,
  • Mitochondrial RNase P protein 2,
  • mitochondrial ribonuclease P protein 2,
  • HCD2,
  • Short-chain type dehydrogenase/reductase XH98G2,
  • MHBD,
  • hydroxyacyl-Coenzyme A dehydrogenase, type II, hydroxyacyl-Coenzyme A dehydrogenase, type II,

View in BioMuta

Description…

HSD17B10, hydroxysteroid (17-beta) dehydrogenase 10, is a member of the short-chain dehydrogenase/reductase superfamily. HSD17B10 functions in mitochondrial tRNA maturation and catalyzes the oxidation of a wide variety of fatty acids, alcohols, and steroids. The protein is thought to play a role in the development of Alzheimer's disease. There are several alternatively spliced transcript variants, of which only two have been fully sequenced.

Attributes

QA State: Curated
Type: Protein
Short Name:
HGNC Name: HSD17B10

Datasets

There are no datasets associated with this biomarker.

Organs

The following organs have data associated with this biomarker…

Breast

Attributes

Phase: Two
QA State: Under Review

Overview

No additional breast data is available.

Performance Comment

HSD17B10 was one of numerous potential early detection biomarkers specific to triple-negative breast cancer in multiple pathways identified.

Studies

This biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact Heather Kincaid at heather.kincaid@jpl.nasa.gov if you should have access to this biomarker.

2015 EDRN PI Orientation

The New and Continuing EDRN Principal Investigator Orientation will take place October 15–16, 2015 in Bethesda, Maryland.

Announcement 06/30/2015

A funding opportunity for a new pancreatic cancer initiative, called The Pancreatic Cancer Detection Consortium (U01), has been released. For more information, please go to http://grants.nih.gov /grants/guide/ pa-files/ PAR-15-289.html.

Announcement 04/08/2015

Thank you to everyone who made the 29th EDRN Steering Committee Meeting a success. The orientation for new and continuing EDRN PIs will be held October 15-16, 2015 on the NCI campus. More information will be available later this summer.