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HSD17B10

Basics

Aliases:
This biomarker is also known as:
  • 3-hydroxy-2-methylbutyryl-CoA dehydrogenase,
  • SDR5C1,
  • HADH2,
  • 17b-HSD10,
  • Mitochondrial ribonuclease P protein 2,
  • amyloid-beta peptide binding alcohol dehydrogenase,
  • 17-beta-hydroxysteroid dehydrogenase 10,
  • mitochondrial ribonuclease P protein 2,
  • DUPXp11.22,
  • 3-hydroxyacyl-CoA dehydrogenase type-2,
  • MRPP2,
  • Endoplasmic reticulum-associated amyloid beta-peptide-binding protein,
  • MRXS10,
  • short chain type dehydrogenase/reductase XH98G2,
  • mitochondrial RNase P subunit 2,
  • AB-binding alcohol dehydrogenase,
  • SCHAD,
  • MRX17,
  • Short-chain type dehydrogenase/reductase XH98G2,
  • endoplasmic reticulum-associated amyloid beta-peptide-binding protein,
  • Mitochondrial RNase P protein 2,
  • HCD2,
  • ERAB,
  • Type II HADH,
  • MHBD,
  • 17-beta-HSD 10,
  • hydroxysteroid (17-beta) dehydrogenase 10,
  • 3-hydroxyacyl-CoA dehydrogenase type II,
  • XH98G2,
  • ABAD,
  • CAMR,
  • MRX31,
  • mental retardation, X-linked, syndromic 10,
  • hydroxyacyl-Coenzyme A dehydrogenase, type II, hydroxyacyl-Coenzyme A dehydrogenase, type II,
  • EC 1.1.1.35,EC 1.1.1.178,
  • short chain L-3-hydroxyacyl-CoA dehydrogenase type 2,
  • short chain dehydrogenase/reductase family 5C, member 1,

View in BioMuta

Description…

HSD17B10, hydroxysteroid (17-beta) dehydrogenase 10, is a member of the short-chain dehydrogenase/reductase superfamily. HSD17B10 functions in mitochondrial tRNA maturation and catalyzes the oxidation of a wide variety of fatty acids, alcohols, and steroids. The protein is thought to play a role in the development of Alzheimer's disease. There are several alternatively spliced transcript variants, of which only two have been fully sequenced.

Attributes

QA State: Curated
Type: Protein
Short Name:
HGNC Name: HSD17B10

Datasets

There are no datasets associated with this biomarker.

Organs

The following organs have data associated with this biomarker…

Breast

Attributes

Phase: Two
QA State: Under Review

Overview

No additional breast data is available.

Performance Comment

HSD17B10 was one of numerous potential early detection biomarkers specific to triple-negative breast cancer in multiple pathways identified.

Studies

This biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact Heather Kincaid at heather.kincaid@jpl.nasa.gov if you should have access to this biomarker.

Announcement 10/07/2014

EDRN Patient Advocates will host an EDRN Advocacy Educational Webinar, Biomarkers for Prostate Cancer Detection and Monitoring, on Monday, January 12th, 2015, at 1 p.m. EDT / 10 a.m. PDT. Registration is not required for this. Please click for more information.
Announcement 09/14/2014

Thank you to everyone who helped make the 9th EDRN Scientific Workshop a success. We look forward to seeing everyone at the 28th EDRN Steering Committee Meeting from March 31-April 2, 2015, in Atlanta, GA.