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This biomarker is also known as:
  • hexamethylene bis-acetamide inducible 1,
  • hexamethylene bisacetamide-inducible protein,
  • HMBA-inducible,
  • menage a quatre protein 1,
  • hexamthylene bis-acetamide inducible 1,
  • CLP-1,
  • Hexamethylene bis-acetamide-inducible protein 1,
  • menage a quatre 1,
  • hexamethylene-bis-acetamide-inducible transcript 1,
  • EDG1,
  • CLP1,
  • HIS1,
  • estrogen down-regulated gene 1 protein,
  • hexamethylene bis-acetamide-inducible protein 1,
  • Menage a quatre protein 1,
  • MAQ1,
  • Cardiac lineage protein 1,
  • cardiac lineage protein 1,
  • Estrogen down-regulated gene 1 protein,
  • protein HEXIM1,

View in BioMuta


HEXIM1 is an intronless transcriptional regulator which functions as a general RNA polymerase II transcription inhibitor. HEXIM1 expression is induced by hexamethylene-bis-acetamide in vascular smooth muscle cells.


QA State: Curated
Type: Protein
Short Name:


There are no datasets associated with this biomarker.


The following organs have data associated with this biomarker…



Phase: Two
QA State: Under Review


No additional breast data available.

Performance Comment

HEXIM1 was one of numerous potential early detection biomarkers specific to triple-negative breast cancer in multiple pathways identified.


This biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact Heather Kincaid at if you should have access to this biomarker.

2016 EDRN PI Orientation

The New and Continuing EDRN Principal Investigator Orientation will take place March 14–15, 2016 in Bethesda, Maryland.

Announcement 11/05/2015

Thank you to everyone who made the 29th EDRN Steering Committee Meeting a success. The orientation for new and continuing EDRN PIs will be held Monday-Tuesday, March 14-15, 2016, on the NCI campus. More information will be available later this autumn.

Announcement 06/30/2015

A funding opportunity for a new pancreatic cancer initiative, called The Pancreatic Cancer Detection Consortium (U01), has been released. For more information, please go to /grants/guide/ pa-files/ PAR-15-289.html.