Skip to content. | Skip to navigation

National Cancer Institute U.S. National Institutes of Health


Personal tools

You are here: Home / Biomarkers / HEXIM1



This biomarker is also known as:
  • cardiac lineage protein 1,
  • HMBA-inducible,
  • hexamethylene bisacetamide-inducible protein,
  • Menage a quatre protein 1,
  • protein HEXIM1,
  • Cardiac lineage protein 1,
  • hexamethylene bis-acetamide inducible 1,
  • CLP1,
  • HIS1,
  • hexamethylene bis-acetamide-inducible protein 1,
  • MAQ1,
  • Estrogen down-regulated gene 1 protein,
  • menage a quatre protein 1,
  • estrogen down-regulated gene 1 protein,
  • Hexamethylene bis-acetamide-inducible protein 1,
  • EDG1,
  • hexamthylene bis-acetamide inducible 1,
  • CLP-1,
  • hexamethylene-bis-acetamide-inducible transcript 1,
  • menage a quatre 1,

View in BioMuta


HEXIM1 is an intronless transcriptional regulator which functions as a general RNA polymerase II transcription inhibitor. HEXIM1 expression is induced by hexamethylene-bis-acetamide in vascular smooth muscle cells.


QA State: Curated
Type: Protein
Short Name:


There are no datasets associated with this biomarker.


The following organs have data associated with this biomarker…



Phase: Two
QA State: Under Review


No additional breast data available.

Performance Comment

HEXIM1 was one of numerous potential early detection biomarkers specific to triple-negative breast cancer in multiple pathways identified.


This biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact Heather Kincaid at if you should have access to this biomarker.

Announcement 10/07/2014

EDRN Patient Advocates will host an EDRN Advocacy Educational Webinar, Biomarkers for Prostate Cancer Detection and Monitoring, on Monday, January 12th, 2015, at 1 p.m. EDT / 10 a.m. PDT. Registration is not required for this. Please click for more information.
Announcement 09/14/2014

Thank you to everyone who helped make the 9th EDRN Scientific Workshop a success. We look forward to seeing everyone at the 28th EDRN Steering Committee Meeting from March 31-April 2, 2015, in Atlanta, GA.