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This biomarker is also known as:
  • frizzled homolog 10 (Drosophila),
  • FzE7,
  • frizzled homolog 10,
  • Fz-10,
  • Q9ULW2,
  • frizzled-10,
  • CD350 antigen,
  • hFz10,
  • CD350,
  • frizzled 10, seven transmembrane spanning receptor,
  • FZ-10,
  • frizzled family receptor 10,
  • Fz10,
  • frizzled (Drosophila) homolog 10,

View in BioMuta


FZD10 is a member of the frizzled gene family. The frizzled gene family encodes 7-transmembrane domain proteins that are receptors for the Wingless type MMTV integration site family of signaling proteins (WNT signaling proteins). The highest levels of expression for FZD10 are seen in the placenta and fetal kidney, followed by fetal lung and brain. Using array analysis, expression of this intronless gene is significantly up-regulated in two cases of primary colon cancer.


QA State: Curated
Type: Protein
Short Name:
HGNC Name: FZD10


There are no datasets associated with this biomarker.


The following organs have data associated with this biomarker…



Phase: Two
QA State: Under Review


FZD10 may be considered for further preclinical testing as a tumor biomarker.

Performance Comment

FZD10 was overexpressed in ovarian cancer relative to normal ovary and relative to a panel of normal organs. FZD10 was detected in vascular structures by in situ hybridization in five independent ovarian cancer samples. FZD10 was found in small and larger blood vessels. FZD10 showed limited or no expression by qRT-PCR in normal tissues.


This biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact Heather Kincaid at if you should have access to this biomarker.

2016 EDRN PI Orientation

The New and Continuing EDRN Principal Investigator Orientation will take place March 14–15, 2016 in Bethesda, Maryland.

Announcement 11/05/2015

Thank you to everyone who made the 29th EDRN Steering Committee Meeting a success. The orientation for new and continuing EDRN PIs will be held Monday-Tuesday, March 14-15, 2016, on the NCI campus. More information will be available later this autumn.

Announcement 06/30/2015

A funding opportunity for a new pancreatic cancer initiative, called The Pancreatic Cancer Detection Consortium (U01), has been released. For more information, please go to /grants/guide/ pa-files/ PAR-15-289.html.