Aliases:This biomarker is also known as:
- Folate receptor alpha,
- Folate receptor 1,
- folate receptor 1 (adult),
- Folate receptor, adult,
- KB cells FBP,
- Adult folate-binding protein,
- Ovarian tumor-associated antigen MOv18,
FOLR1 is a cell membrane protein that binds to folate and reduced folic acid derivatives and mediates delivery of 5-methyltetrahydrofolate to the interior of cells. It is a secreted protein that either anchors to membranes via a glycosyl-phosphatidylinositol linkage or exists in a soluble form. Mutations in this gene have been associated with neurodegeneration due to cerebral folate transport deficiency.
|QA State:||Under Review|
There are no datasets associated with this biomarker.