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ECM1

Basics

Aliases:
This biomarker is also known as:
  • Secretory component p85,
  • extracellular matrix protein 1,

View in BioMuta

Description…

ECM1 is an extracellular protein containing motifs with a cysteine pattern characteristic of the cysteine pattern of the ligand-binding "double-loop" domains of the albumin protein family. It is involved in endochondral bone formation as negative regulator of bone mineralization. EMC1 stimulates the proliferation of endothelial cells and promotes angiogenesis. It also inhibits MMP9 proteolytic activity. ECM1 is expressed in breast cancer tissues, however little or no expression observed in normal breast tissues. It is also expressed in skin; wide expression is observed throughout the dermis with minimal expression in the epidermis.

Attributes

QA State: Curated
Type: Protein
Short Name:
HGNC Name: ECM1

Datasets

There are no datasets associated with this biomarker.

Organs

The following organs have data associated with this biomarker…

Ovary

Attributes

Phase: One
QA State: Curated

Overview

Performance Comment

Studies

This biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact Heather Kincaid at heather.kincaid@jpl.nasa.gov if you should have access to this biomarker.

Publications

No associated publications found.

Resources

No associated resources found.

Announcement 10/07/2014

EDRN Patient Advocates will host an EDRN Advocacy Educational Webinar, Biomarkers for Prostate Cancer Detection and Monitoring, on Monday, January 12th, 2015, at 1 p.m. EDT / 10 a.m. PDT. Registration is not required for this. Please click for more information.
Announcement 09/14/2014

Thank you to everyone who helped make the 9th EDRN Scientific Workshop a success. We look forward to seeing everyone at the 28th EDRN Steering Committee Meeting from March 31-April 2, 2015, in Atlanta, GA.