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DNAJC7

Basics

Aliases:
This biomarker is also known as:
  • DJ11,
  • DnaJ (Hsp40) homolog, subfamily C, member 7,
  • TPR repeat protein 2,
  • TTC2,
  • DJC7,
  • DANJC7,
  • tetratricopeptide repeat domain 2,
  • tetratricopeptide repeat protein 2,
  • dnaJ homolog subfamily C member 7,
  • Tetratricopeptide repeat protein 2,
  • TPR2,

View in BioMuta

Description…

DNAJC7 is a member of the DNAJ heat shock protein 40 family. This family is characterized by two N-terminal tetratricopeptide repeat domains and a C-terminal DNAJ domain. DNAJC7 functions as a co-chaperone regulating the molecular chaperones HSP70 and HSP90 in folding of steroid receptors, such as the glucocorticoid receptor and the progesterone receptor. There are pseudogenes of this gene on chromosomes 1 and 6. Multiple transcript variants of DNAJC7 exist from alternate splicing.

Attributes

QA State: Curated
Type: Protein
Short Name:
HGNC Name: DNAJC7

Datasets

There are no datasets associated with this biomarker.

Organs

The following organs have data associated with this biomarker…

Breast

Attributes

Phase: Two
QA State: Under Review

Overview

No additional breast data available.

Performance Comment

DNAJC7 was one of numerous potential early detection biomarkers specific to triple-negative breast cancer in multiple pathways identified.

Studies

This biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact Heather Kincaid at heather.kincaid@jpl.nasa.gov if you should have access to this biomarker.

2015 EDRN PI Orientation

The New and Continuing EDRN Principal Investigator Orientation will take place October 15–16, 2015 in Bethesda, Maryland.

Announcement 06/30/2015

A funding opportunity for a new pancreatic cancer initiative, called The Pancreatic Cancer Detection Consortium (U01), has been released. For more information, please go to http://grants.nih.gov /grants/guide/ pa-files/ PAR-15-289.html.

Announcement 04/08/2015

Thank you to everyone who made the 29th EDRN Steering Committee Meeting a success. The orientation for new and continuing EDRN PIs will be held October 15-16, 2015 on the NCI campus. More information will be available later this summer.