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This biomarker is also known as:
  • DiGeorge syndrome critical region 6,
  • protein DGCR6,
  • DiGeorge syndrome critical region protein 6,
  • DiGeorge syndrome critical region gene 6,

View in BioMuta


DGCR6 is located on chromosome 22q11.21. Microdeletions in this region are associated with DiGeorge syndrome, and more widely, the CATCH 22 syndrome. DGCR6, also known as DiGeorge syndrome critical region 6, is thought to be involved in DiGeorge syndrome pathology and in schizophrenia. Another function attributed to this gene is a role in neural crest cell migration into the third and fourth pharyngeal pouches. The DGCR6 protein shares homology with the Drosophila melanogaster gonadal protein, which participates in gonadal and germ cell development, and with the gamma-1 subunit of human laminin.


QA State: Curated
Type: Protein
Short Name:


There are no datasets associated with this biomarker.


The following organs have data associated with this biomarker…



Phase: Two
QA State: Under Review


No additional breast data available.

Performance Comment

DGCR6 was one of numerous potential early detection biomarkers specific to triple-negative breast cancer in multiple pathways identified.


This biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact Heather Kincaid at if you should have access to this biomarker.

2016 EDRN PI Orientation

The New and Continuing EDRN Principal Investigator Orientation will take place March 14–15, 2016 in Bethesda, Maryland.

Announcement 11/05/2015

Thank you to everyone who made the 29th EDRN Steering Committee Meeting a success. The orientation for new and continuing EDRN PIs will be held Monday-Tuesday, March 14-15, 2016, on the NCI campus. More information will be available later this autumn.

Announcement 06/30/2015

A funding opportunity for a new pancreatic cancer initiative, called The Pancreatic Cancer Detection Consortium (U01), has been released. For more information, please go to /grants/guide/ pa-files/ PAR-15-289.html.